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• W2057143539 startingPage "20801" @default.
• W2057143539 abstract "Significance The blood–brain barrier (BBB) prevents ingress of small molecules into the brain partly by expression of drug efflux transporters. Although several transporters are known to be involved, the role ABCG2 plays in this process is not clear. We demonstrate the ability to image ABCG2 function at the BBB by using luciferin in a luciferase-expressing mouse. This represents a direct measurement of ABCG2 function at the BBB, and demonstrates that ABCG2 does play a functional role at the BBB." @default.
• W2057143539 created "2016-06-24" @default.
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• W2057143539 date "2013-12-02" @default.
• W2057143539 modified "2023-09-24" @default.
• W2057143539 title "Bioluminescent imaging of drug efflux at the blood–brain barrier mediated by the transporter ABCG2" @default.
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• W2057143539 doi "https://doi.org/10.1073/pnas.1312159110" @default.
• W2057143539 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3870704" @default.
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