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- W2057175161 abstract "Measurements of the forces between supported bilayers containing the ganglioside GM1 (monosialoganglioside) are reported. The interaction between pure GM1 bilayers bathed in 1 mM sodium chloride is well described by DLVO theory at large separations. At 100 m M sodium chloride a weak attractive minimum due to a van der Waals force is measured outside the range of the double layer interaction. When GM1 is mixed with dioleoylphosphatidylcholine (DOPC) the force is again well fitted by double layer theory at large separations. A hard wall in the force is encountered at 4.5 nm which is the separation at which the hydration force from DOPC is expected. The interactions between GM1 layers mixed with dipalmitoylphosphotidylcholine (DPPC) shows a hard wall in the force curve at a much larger separation (8–9.3 nm). The force in all cases remained repulsive at small separations although DLVO theory predicts an attraction due to van der Waals forces. It is proposed that loss of this attraction is due to a combination of hydration and steric repulsion and as a result GM1 alone cannot promote adhesion between bilayers." @default.
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- W2057175161 date "1990-07-01" @default.
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- W2057175161 title "Forces between bilayers containing charged glycolipids" @default.
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- W2057175161 doi "https://doi.org/10.1016/0021-9797(90)90430-v" @default.
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