Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057188090> ?p ?o ?g. }
- W2057188090 endingPage "2286" @default.
- W2057188090 startingPage "2277" @default.
- W2057188090 abstract "ABSTRACT Bone morphogenetic protein 4 (BMP4) and retinoic acid are important for normal development of the inner ear, but whether they are linked mechanistically is not known. BMP4 antagonists disrupt semicircular canal formation, as does exposure to retinoic acid. We demonstrate that retinoic acid directly down-regulates BMP4 transcription in a mouse inner ear-derived cell line, and we identify a novel promoter in the second intron of the BMP4 gene that is a target of this regulation both in the cell line and in the mouse embryonic inner ear in vivo. The importance of this down-regulation is demonstrated in chicken embryos by showing that the retinoic acid effect on semicircular canal development can be overcome by exogenous BMP4." @default.
- W2057188090 created "2016-06-24" @default.
- W2057188090 creator A5023871336 @default.
- W2057188090 creator A5039491508 @default.
- W2057188090 creator A5048412798 @default.
- W2057188090 creator A5088948001 @default.
- W2057188090 date "2003-04-01" @default.
- W2057188090 modified "2023-10-16" @default.
- W2057188090 title "Retinoic Acid Repression of Bone Morphogenetic Protein 4 in Inner Ear Development" @default.
- W2057188090 cites W102030471 @default.
- W2057188090 cites W1493100105 @default.
- W2057188090 cites W1658389211 @default.
- W2057188090 cites W1890207703 @default.
- W2057188090 cites W1910819802 @default.
- W2057188090 cites W1944595096 @default.
- W2057188090 cites W1953633452 @default.
- W2057188090 cites W1965045361 @default.
- W2057188090 cites W1970517203 @default.
- W2057188090 cites W1971624992 @default.
- W2057188090 cites W1973209839 @default.
- W2057188090 cites W1979518793 @default.
- W2057188090 cites W1983919142 @default.
- W2057188090 cites W1984509210 @default.
- W2057188090 cites W1986469118 @default.
- W2057188090 cites W2012279861 @default.
- W2057188090 cites W2012737818 @default.
- W2057188090 cites W2015091248 @default.
- W2057188090 cites W2023501354 @default.
- W2057188090 cites W2025267983 @default.
- W2057188090 cites W2032531547 @default.
- W2057188090 cites W2041270901 @default.
- W2057188090 cites W2048757240 @default.
- W2057188090 cites W2053131171 @default.
- W2057188090 cites W2055110202 @default.
- W2057188090 cites W2061635281 @default.
- W2057188090 cites W2067884021 @default.
- W2057188090 cites W2068458442 @default.
- W2057188090 cites W2068796796 @default.
- W2057188090 cites W2080847784 @default.
- W2057188090 cites W2086972110 @default.
- W2057188090 cites W2107052606 @default.
- W2057188090 cites W2107141327 @default.
- W2057188090 cites W2110795525 @default.
- W2057188090 cites W2122828787 @default.
- W2057188090 cites W2136479777 @default.
- W2057188090 cites W2141568746 @default.
- W2057188090 cites W2145221641 @default.
- W2057188090 cites W2327390910 @default.
- W2057188090 cites W2337949001 @default.
- W2057188090 cites W79238280 @default.
- W2057188090 doi "https://doi.org/10.1128/mcb.23.7.2277-2286.2003" @default.
- W2057188090 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/150746" @default.
- W2057188090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12640113" @default.
- W2057188090 hasPublicationYear "2003" @default.
- W2057188090 type Work @default.
- W2057188090 sameAs 2057188090 @default.
- W2057188090 citedByCount "59" @default.
- W2057188090 countsByYear W20571880902012 @default.
- W2057188090 countsByYear W20571880902013 @default.
- W2057188090 countsByYear W20571880902014 @default.
- W2057188090 countsByYear W20571880902015 @default.
- W2057188090 countsByYear W20571880902016 @default.
- W2057188090 countsByYear W20571880902018 @default.
- W2057188090 countsByYear W20571880902019 @default.
- W2057188090 countsByYear W20571880902020 @default.
- W2057188090 countsByYear W20571880902021 @default.
- W2057188090 countsByYear W20571880902023 @default.
- W2057188090 crossrefType "journal-article" @default.
- W2057188090 hasAuthorship W2057188090A5023871336 @default.
- W2057188090 hasAuthorship W2057188090A5039491508 @default.
- W2057188090 hasAuthorship W2057188090A5048412798 @default.
- W2057188090 hasAuthorship W2057188090A5088948001 @default.
- W2057188090 hasBestOaLocation W20571880901 @default.
- W2057188090 hasConcept C104317684 @default.
- W2057188090 hasConcept C150194340 @default.
- W2057188090 hasConcept C186310378 @default.
- W2057188090 hasConcept C202751555 @default.
- W2057188090 hasConcept C2779963572 @default.
- W2057188090 hasConcept C2781121885 @default.
- W2057188090 hasConcept C30352789 @default.
- W2057188090 hasConcept C31507581 @default.
- W2057188090 hasConcept C54355233 @default.
- W2057188090 hasConcept C86803240 @default.
- W2057188090 hasConcept C95444343 @default.
- W2057188090 hasConceptScore W2057188090C104317684 @default.
- W2057188090 hasConceptScore W2057188090C150194340 @default.
- W2057188090 hasConceptScore W2057188090C186310378 @default.
- W2057188090 hasConceptScore W2057188090C202751555 @default.
- W2057188090 hasConceptScore W2057188090C2779963572 @default.
- W2057188090 hasConceptScore W2057188090C2781121885 @default.
- W2057188090 hasConceptScore W2057188090C30352789 @default.
- W2057188090 hasConceptScore W2057188090C31507581 @default.
- W2057188090 hasConceptScore W2057188090C54355233 @default.
- W2057188090 hasConceptScore W2057188090C86803240 @default.
- W2057188090 hasConceptScore W2057188090C95444343 @default.
- W2057188090 hasIssue "7" @default.
- W2057188090 hasLocation W20571880901 @default.
- W2057188090 hasLocation W20571880902 @default.