FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057194771> ?p ?o ?g. }

• W2057194771 endingPage "90" @default.
• W2057194771 startingPage "84" @default.
• W2057194771 abstract "Certain arachidonic acid metabolites, including prostaglandins (PGs) E1 and E2, have been shown to exert marked immunosuppressive effects on T-cell and macrophage functions. Cyclooxygenase blockade with indomethacin or ibuprofen may ameloriate these effects. In the current study we measured lymphocyte proliferation by thymidine incorporation, the presence of T-cell activation antigens with monoclonal antibodies and two-color flow cytometry, and neutrophil (PMN) oxidative burst using a fluorescent marker, in control mice and in burned mice treated with indomethacin for 10 days after injury. One-half of the cell cultures were treated with indomethacin in vitro to ensure its continued presence during stimulation. Separate groups of mice were fed a fish oil-based diet which leads to the production of PGE3 rather than PGE2, versus standard mouse chow, a soy-bean oil-based diet which leads to PGE2 production. Lymphocyte proliferation, expression of T-cell activation antigens, and PMN oxidative burst remained depressed in burned mice treated with indomethacin in vivo (plus in vitro) and in those which received the fish oil-based diet, compared to control. Blockade of PG synthesis after murine burn injury by cyclooxygenase inhibition or alterations in the diet failed to restore T-lymphocyte activation or proliferation or to improve PMN oxidative burst. These data suggest that PGE2 alone does not explain the immunosuppression noted after burn injury." @default.
• W2057194771 created "2016-06-24" @default.
• W2057194771 creator A5019025611 @default.
• W2057194771 creator A5046623395 @default.
• W2057194771 date "1990-01-01" @default.
• W2057194771 modified "2023-10-08" @default.
• W2057194771 title "Postburn suppression of murine lymphocyte and neutrophil functions is not reversed by prostaglandin blockade" @default.
• W2057194771 cites W1510122008 @default.
• W2057194771 cites W1957021982 @default.
• W2057194771 cites W1965416209 @default.
• W2057194771 cites W1968577625 @default.
• W2057194771 cites W1971661892 @default.
• W2057194771 cites W1974609135 @default.
• W2057194771 cites W1977380444 @default.
• W2057194771 cites W1979380990 @default.
• W2057194771 cites W1979665105 @default.
• W2057194771 cites W1989924463 @default.
• W2057194771 cites W1992148976 @default.
• W2057194771 cites W1992702451 @default.
• W2057194771 cites W1999095506 @default.
• W2057194771 cites W2004351423 @default.
• W2057194771 cites W2009080391 @default.
• W2057194771 cites W2009617509 @default.
• W2057194771 cites W2018239785 @default.
• W2057194771 cites W2018911643 @default.
• W2057194771 cites W2024897521 @default.
• W2057194771 cites W2028100397 @default.
• W2057194771 cites W2037267173 @default.
• W2057194771 cites W2057013816 @default.
• W2057194771 cites W2068825762 @default.
• W2057194771 cites W2069618594 @default.
• W2057194771 cites W2086555858 @default.
• W2057194771 cites W2087792935 @default.
• W2057194771 cites W2092830270 @default.
• W2057194771 cites W2124413774 @default.
• W2057194771 cites W2148190114 @default.
• W2057194771 cites W2154229831 @default.
• W2057194771 cites W2169503365 @default.
• W2057194771 cites W2177594905 @default.
• W2057194771 cites W238978741 @default.
• W2057194771 cites W2996836182 @default.
• W2057194771 cites W4239261179 @default.
• W2057194771 cites W4248564216 @default.
• W2057194771 cites W4249058396 @default.
• W2057194771 cites W4292670498 @default.
• W2057194771 doi "https://doi.org/10.1016/0022-4804(90)90151-q" @default.
• W2057194771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2296186" @default.
• W2057194771 hasPublicationYear "1990" @default.
• W2057194771 type Work @default.
• W2057194771 sameAs 2057194771 @default.
• W2057194771 citedByCount "15" @default.
• W2057194771 crossrefType "journal-article" @default.
• W2057194771 hasAuthorship W2057194771A5019025611 @default.
• W2057194771 hasAuthorship W2057194771A5046623395 @default.
• W2057194771 hasConcept C126322002 @default.
• W2057194771 hasConcept C134018914 @default.
• W2057194771 hasConcept C150903083 @default.
• W2057194771 hasConcept C170493617 @default.
• W2057194771 hasConcept C181199279 @default.
• W2057194771 hasConcept C203014093 @default.
• W2057194771 hasConcept C207001950 @default.
• W2057194771 hasConcept C2777198256 @default.
• W2057194771 hasConcept C2777761686 @default.
• W2057194771 hasConcept C2777956040 @default.
• W2057194771 hasConcept C2778078955 @default.
• W2057194771 hasConcept C2778468042 @default.
• W2057194771 hasConcept C2779689624 @default.
• W2057194771 hasConcept C55493867 @default.
• W2057194771 hasConcept C71924100 @default.
• W2057194771 hasConcept C86803240 @default.
• W2057194771 hasConcept C98274493 @default.
• W2057194771 hasConcept C99971728 @default.
• W2057194771 hasConceptScore W2057194771C126322002 @default.
• W2057194771 hasConceptScore W2057194771C134018914 @default.
• W2057194771 hasConceptScore W2057194771C150903083 @default.
• W2057194771 hasConceptScore W2057194771C170493617 @default.
• W2057194771 hasConceptScore W2057194771C181199279 @default.
• W2057194771 hasConceptScore W2057194771C203014093 @default.
• W2057194771 hasConceptScore W2057194771C207001950 @default.
• W2057194771 hasConceptScore W2057194771C2777198256 @default.
• W2057194771 hasConceptScore W2057194771C2777761686 @default.
• W2057194771 hasConceptScore W2057194771C2777956040 @default.
• W2057194771 hasConceptScore W2057194771C2778078955 @default.
• W2057194771 hasConceptScore W2057194771C2778468042 @default.
• W2057194771 hasConceptScore W2057194771C2779689624 @default.
• W2057194771 hasConceptScore W2057194771C55493867 @default.
• W2057194771 hasConceptScore W2057194771C71924100 @default.
• W2057194771 hasConceptScore W2057194771C86803240 @default.
• W2057194771 hasConceptScore W2057194771C98274493 @default.
• W2057194771 hasConceptScore W2057194771C99971728 @default.
• W2057194771 hasIssue "1" @default.
• W2057194771 hasLocation W20571947711 @default.
• W2057194771 hasLocation W20571947712 @default.
• W2057194771 hasOpenAccess W2057194771 @default.
• W2057194771 hasPrimaryLocation W20571947711 @default.
• W2057194771 hasRelatedWork W1968233993 @default.
• W2057194771 hasRelatedWork W2005860484 @default.
• W2057194771 hasRelatedWork W2050532610 @default.

• next