Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057202428> ?p ?o ?g. }
- W2057202428 endingPage "492" @default.
- W2057202428 startingPage "485" @default.
- W2057202428 abstract "Multiplex genetic testing, including both moderate- and high-penetrance genes for cancer susceptibility, is associated with greater uncertainty than traditional testing, presenting challenges to informed consent and genetic counseling. We sought to develop a new model for informed consent and genetic counseling for four ongoing studies.Drawing from professional guidelines, literature, conceptual frameworks, and clinical experience, a multidisciplinary group developed a tiered-binned genetic counseling approach proposed to facilitate informed consent and improve outcomes of cancer susceptibility multiplex testing.In this model, tier 1 indispensable information is presented to all patients. More specific tier 2 information is provided to support variable informational needs among diverse patient populations. Clinically relevant information is binned into groups to minimize information overload, support informed decision making, and facilitate adaptive responses to testing. Seven essential elements of informed consent are provided to address the unique limitations, risks, and uncertainties of multiplex testing.A tiered-binned model for informed consent and genetic counseling has the potential to address the challenges of multiplex testing for cancer susceptibility and to support informed decision making and adaptive responses to testing. Future prospective studies including patient-reported outcomes are needed to inform how to best incorporate multiplex testing for cancer susceptibility into clinical practice.Genet Med 17 6, 485-492." @default.
- W2057202428 created "2016-06-24" @default.
- W2057202428 creator A5003759103 @default.
- W2057202428 creator A5004070770 @default.
- W2057202428 creator A5005021341 @default.
- W2057202428 creator A5005752442 @default.
- W2057202428 creator A5009072858 @default.
- W2057202428 creator A5015295496 @default.
- W2057202428 creator A5016775702 @default.
- W2057202428 creator A5017604098 @default.
- W2057202428 creator A5018722278 @default.
- W2057202428 creator A5021967621 @default.
- W2057202428 creator A5022322037 @default.
- W2057202428 creator A5031560294 @default.
- W2057202428 creator A5032695297 @default.
- W2057202428 creator A5034262776 @default.
- W2057202428 creator A5041518416 @default.
- W2057202428 creator A5045057913 @default.
- W2057202428 creator A5046217844 @default.
- W2057202428 creator A5048962870 @default.
- W2057202428 creator A5052221383 @default.
- W2057202428 creator A5056325723 @default.
- W2057202428 creator A5057209864 @default.
- W2057202428 creator A5057938823 @default.
- W2057202428 creator A5061783891 @default.
- W2057202428 creator A5063299870 @default.
- W2057202428 creator A5064418448 @default.
- W2057202428 creator A5069505058 @default.
- W2057202428 creator A5076567963 @default.
- W2057202428 creator A5076948171 @default.
- W2057202428 creator A5090965905 @default.
- W2057202428 creator A5091867823 @default.
- W2057202428 date "2015-06-01" @default.
- W2057202428 modified "2023-10-17" @default.
- W2057202428 title "Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility" @default.
- W2057202428 cites W1481439235 @default.
- W2057202428 cites W1536226887 @default.
- W2057202428 cites W1826395735 @default.
- W2057202428 cites W1967895150 @default.
- W2057202428 cites W1968713551 @default.
- W2057202428 cites W1977398574 @default.
- W2057202428 cites W1978028039 @default.
- W2057202428 cites W1982348997 @default.
- W2057202428 cites W1988656726 @default.
- W2057202428 cites W1992625057 @default.
- W2057202428 cites W1993022398 @default.
- W2057202428 cites W1995730962 @default.
- W2057202428 cites W1999077228 @default.
- W2057202428 cites W2002150942 @default.
- W2057202428 cites W2010378709 @default.
- W2057202428 cites W2016610070 @default.
- W2057202428 cites W2025614131 @default.
- W2057202428 cites W2026996795 @default.
- W2057202428 cites W2037945778 @default.
- W2057202428 cites W2063303386 @default.
- W2057202428 cites W2072051652 @default.
- W2057202428 cites W2074177828 @default.
- W2057202428 cites W2076621898 @default.
- W2057202428 cites W2092373383 @default.
- W2057202428 cites W2093022647 @default.
- W2057202428 cites W2095787833 @default.
- W2057202428 cites W2102766081 @default.
- W2057202428 cites W2106542343 @default.
- W2057202428 cites W2115575604 @default.
- W2057202428 cites W2117576401 @default.
- W2057202428 cites W2139415509 @default.
- W2057202428 cites W2142906250 @default.
- W2057202428 cites W2155527348 @default.
- W2057202428 cites W2163633684 @default.
- W2057202428 cites W2165023188 @default.
- W2057202428 cites W2167564136 @default.
- W2057202428 cites W2171718922 @default.
- W2057202428 cites W2473509060 @default.
- W2057202428 cites W4239330620 @default.
- W2057202428 doi "https://doi.org/10.1038/gim.2014.134" @default.
- W2057202428 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4983405" @default.
- W2057202428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25297947" @default.
- W2057202428 hasPublicationYear "2015" @default.
- W2057202428 type Work @default.
- W2057202428 sameAs 2057202428 @default.
- W2057202428 citedByCount "71" @default.
- W2057202428 countsByYear W20572024282015 @default.
- W2057202428 countsByYear W20572024282016 @default.
- W2057202428 countsByYear W20572024282017 @default.
- W2057202428 countsByYear W20572024282018 @default.
- W2057202428 countsByYear W20572024282019 @default.
- W2057202428 countsByYear W20572024282020 @default.
- W2057202428 countsByYear W20572024282021 @default.
- W2057202428 countsByYear W20572024282022 @default.
- W2057202428 countsByYear W20572024282023 @default.
- W2057202428 crossrefType "journal-article" @default.
- W2057202428 hasAuthorship W2057202428A5003759103 @default.
- W2057202428 hasAuthorship W2057202428A5004070770 @default.
- W2057202428 hasAuthorship W2057202428A5005021341 @default.
- W2057202428 hasAuthorship W2057202428A5005752442 @default.
- W2057202428 hasAuthorship W2057202428A5009072858 @default.
- W2057202428 hasAuthorship W2057202428A5015295496 @default.
- W2057202428 hasAuthorship W2057202428A5016775702 @default.