FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057202459> ?p ?o ?g. }

• W2057202459 endingPage "311" @default.
• W2057202459 startingPage "301" @default.
• W2057202459 abstract "Ischemia is an important etiology of painful neuropathies. We generated a mouse system of ischemic neuropathy by ligation-reperfusion of the femoral artery to mimic neuropathic pain and nerve injury patterns observed clinically. Mice exhibited spontaneous neuropathic pain behaviors, which were most obvious after ischemia for 5 h. Mechanical and cold allodynia developed by post-operative day (POD) 7 and persisted through the experimental period up to POD 56. Neuropathic pain behaviors were alleviated with intraperitoneal gabapentin (50 and 100 mg/kg) in a dose-dependent manner. Large-fiber deficit assessed with nerve conduction studies was demonstrated by reduced amplitudes of the compound muscle action potential (CMAP) on POD 7 (48.4% of the control side, p < 0.001). Small-fiber impairment was demonstrated by decreased epidermal nerve density (END) on POD 7 (29.1% of the control side, p < 0.001). Reductions in CMAP amplitudes and ENDs persisted through POD 56. Our system replicated the clinical manifestations of ischemic neuropathy: (1) neuropathic pain with cold and mechanical allodynia and (2) nerve injury to both large and small fibers with pathologic and physiologic evidence. This system produced by a simple procedure provides an opportunity to investigate mechanisms and further treatments of ischemic neuropathy on genetically engineered mice." @default.
• W2057202459 created "2016-06-24" @default.
• W2057202459 creator A5034401376 @default.
• W2057202459 creator A5041552063 @default.
• W2057202459 creator A5057622632 @default.
• W2057202459 creator A5066252069 @default.
• W2057202459 creator A5070394837 @default.
• W2057202459 date "2012-09-01" @default.
• W2057202459 modified "2023-09-27" @default.
• W2057202459 title "Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice" @default.
• W2057202459 cites W1966774827 @default.
• W2057202459 cites W1973982249 @default.
• W2057202459 cites W1975585602 @default.
• W2057202459 cites W1981748801 @default.
• W2057202459 cites W1994407350 @default.
• W2057202459 cites W1995061216 @default.
• W2057202459 cites W1998407360 @default.
• W2057202459 cites W2002312214 @default.
• W2057202459 cites W2004617102 @default.
• W2057202459 cites W2019822009 @default.
• W2057202459 cites W2033914476 @default.
• W2057202459 cites W2035147973 @default.
• W2057202459 cites W2039519643 @default.
• W2057202459 cites W2049938995 @default.
• W2057202459 cites W2058020736 @default.
• W2057202459 cites W2066346649 @default.
• W2057202459 cites W2067924690 @default.
• W2057202459 cites W2071862338 @default.
• W2057202459 cites W2079692119 @default.
• W2057202459 cites W2082885661 @default.
• W2057202459 cites W2084465451 @default.
• W2057202459 cites W2087454739 @default.
• W2057202459 cites W2088984312 @default.
• W2057202459 cites W2092822928 @default.
• W2057202459 cites W2094267095 @default.
• W2057202459 cites W2103289098 @default.
• W2057202459 cites W2129219475 @default.
• W2057202459 cites W2141115412 @default.
• W2057202459 cites W2142295577 @default.
• W2057202459 cites W2151359347 @default.
• W2057202459 cites W2156264261 @default.
• W2057202459 cites W2159220940 @default.
• W2057202459 cites W2169704215 @default.
• W2057202459 cites W2172201406 @default.
• W2057202459 cites W2188137227 @default.
• W2057202459 cites W264893331 @default.
• W2057202459 cites W4248263001 @default.
• W2057202459 doi "https://doi.org/10.1111/j.1529-8027.2012.00418.x" @default.
• W2057202459 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22971092" @default.
• W2057202459 hasPublicationYear "2012" @default.
• W2057202459 type Work @default.
• W2057202459 sameAs 2057202459 @default.
• W2057202459 citedByCount "8" @default.
• W2057202459 countsByYear W20572024592015 @default.
• W2057202459 countsByYear W20572024592016 @default.
• W2057202459 countsByYear W20572024592017 @default.
• W2057202459 countsByYear W20572024592019 @default.
• W2057202459 countsByYear W20572024592021 @default.
• W2057202459 countsByYear W20572024592022 @default.
• W2057202459 countsByYear W20572024592023 @default.
• W2057202459 crossrefType "journal-article" @default.
• W2057202459 hasAuthorship W2057202459A5034401376 @default.
• W2057202459 hasAuthorship W2057202459A5041552063 @default.
• W2057202459 hasAuthorship W2057202459A5057622632 @default.
• W2057202459 hasAuthorship W2057202459A5066252069 @default.
• W2057202459 hasAuthorship W2057202459A5070394837 @default.
• W2057202459 hasConcept C126322002 @default.
• W2057202459 hasConcept C141071460 @default.
• W2057202459 hasConcept C142724271 @default.
• W2057202459 hasConcept C151626666 @default.
• W2057202459 hasConcept C15490471 @default.
• W2057202459 hasConcept C170493617 @default.
• W2057202459 hasConcept C179437574 @default.
• W2057202459 hasConcept C185263204 @default.
• W2057202459 hasConcept C204787440 @default.
• W2057202459 hasConcept C2775991916 @default.
• W2057202459 hasConcept C2776608144 @default.
• W2057202459 hasConcept C2777107010 @default.
• W2057202459 hasConcept C2777883359 @default.
• W2057202459 hasConcept C2779245659 @default.
• W2057202459 hasConcept C42219234 @default.
• W2057202459 hasConcept C541997718 @default.
• W2057202459 hasConcept C71924100 @default.
• W2057202459 hasConceptScore W2057202459C126322002 @default.
• W2057202459 hasConceptScore W2057202459C141071460 @default.
• W2057202459 hasConceptScore W2057202459C142724271 @default.
• W2057202459 hasConceptScore W2057202459C151626666 @default.
• W2057202459 hasConceptScore W2057202459C15490471 @default.
• W2057202459 hasConceptScore W2057202459C170493617 @default.
• W2057202459 hasConceptScore W2057202459C179437574 @default.
• W2057202459 hasConceptScore W2057202459C185263204 @default.
• W2057202459 hasConceptScore W2057202459C204787440 @default.
• W2057202459 hasConceptScore W2057202459C2775991916 @default.
• W2057202459 hasConceptScore W2057202459C2776608144 @default.
• W2057202459 hasConceptScore W2057202459C2777107010 @default.
• W2057202459 hasConceptScore W2057202459C2777883359 @default.
• W2057202459 hasConceptScore W2057202459C2779245659 @default.
• W2057202459 hasConceptScore W2057202459C42219234 @default.

• next