Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057205964> ?p ?o ?g. }
- W2057205964 abstract "Defective paracrine Transforming Growth Factor-β TGF-β) signaling between endothelial cells and the neighboring mural cells have been thought to lead to the development of vascular lesions that are characteristic of Hereditary Hemorrhagic Telangiectasia (HHT). This review highlights recent progress in our understanding of TGF-β signaling in mural cell recruitment and vessel stabilization and how perturbed TGF-β signaling might contribute to defective endothelial-mural cell interaction affecting vessel functionalities. Our recent findings have provided exciting insights into the role of thalidomide, a drug that reduces both the frequency and the duration of epistaxis in individuals with HHT by targeting mural cells. These advances provide opportunities for the development of new therapies for vascular malformations." @default.
- W2057205964 created "2016-06-24" @default.
- W2057205964 creator A5051185238 @default.
- W2057205964 creator A5058401645 @default.
- W2057205964 creator A5063955833 @default.
- W2057205964 date "2015-02-13" @default.
- W2057205964 modified "2023-10-17" @default.
- W2057205964 title "Pericytes as targets in hereditary hemorrhagic telangiectasia" @default.
- W2057205964 cites W111650051 @default.
- W2057205964 cites W1260393137 @default.
- W2057205964 cites W1540540538 @default.
- W2057205964 cites W156646843 @default.
- W2057205964 cites W1576609386 @default.
- W2057205964 cites W1931073059 @default.
- W2057205964 cites W1963782060 @default.
- W2057205964 cites W1964513396 @default.
- W2057205964 cites W1970122794 @default.
- W2057205964 cites W1970826769 @default.
- W2057205964 cites W1971012582 @default.
- W2057205964 cites W1971162717 @default.
- W2057205964 cites W1971951473 @default.
- W2057205964 cites W1975522586 @default.
- W2057205964 cites W1977046091 @default.
- W2057205964 cites W1978003340 @default.
- W2057205964 cites W1978999523 @default.
- W2057205964 cites W1979826838 @default.
- W2057205964 cites W1982506421 @default.
- W2057205964 cites W1985147506 @default.
- W2057205964 cites W1985186457 @default.
- W2057205964 cites W1987208604 @default.
- W2057205964 cites W1988613013 @default.
- W2057205964 cites W1992112921 @default.
- W2057205964 cites W1993523135 @default.
- W2057205964 cites W1994481502 @default.
- W2057205964 cites W1995387334 @default.
- W2057205964 cites W1995964124 @default.
- W2057205964 cites W1997538895 @default.
- W2057205964 cites W1997952190 @default.
- W2057205964 cites W1998913198 @default.
- W2057205964 cites W1999470499 @default.
- W2057205964 cites W2001552996 @default.
- W2057205964 cites W2002392082 @default.
- W2057205964 cites W2002569536 @default.
- W2057205964 cites W2002621910 @default.
- W2057205964 cites W2003561988 @default.
- W2057205964 cites W2005259727 @default.
- W2057205964 cites W2005753063 @default.
- W2057205964 cites W2006264351 @default.
- W2057205964 cites W2010640441 @default.
- W2057205964 cites W2013160042 @default.
- W2057205964 cites W2013692456 @default.
- W2057205964 cites W2014415717 @default.
- W2057205964 cites W2016140581 @default.
- W2057205964 cites W2017838785 @default.
- W2057205964 cites W2018860781 @default.
- W2057205964 cites W2019453487 @default.
- W2057205964 cites W2020019369 @default.
- W2057205964 cites W2021605609 @default.
- W2057205964 cites W2022415270 @default.
- W2057205964 cites W2025823855 @default.
- W2057205964 cites W2030620101 @default.
- W2057205964 cites W2030662016 @default.
- W2057205964 cites W2030717725 @default.
- W2057205964 cites W2030828634 @default.
- W2057205964 cites W2032287326 @default.
- W2057205964 cites W2032686344 @default.
- W2057205964 cites W2035005764 @default.
- W2057205964 cites W2035282407 @default.
- W2057205964 cites W2036178809 @default.
- W2057205964 cites W2038304860 @default.
- W2057205964 cites W2040008417 @default.
- W2057205964 cites W2041617294 @default.
- W2057205964 cites W2042698075 @default.
- W2057205964 cites W2045851446 @default.
- W2057205964 cites W2046318702 @default.
- W2057205964 cites W2046443713 @default.
- W2057205964 cites W2049203485 @default.
- W2057205964 cites W2049460778 @default.
- W2057205964 cites W2051726431 @default.
- W2057205964 cites W2051816002 @default.
- W2057205964 cites W2056856515 @default.
- W2057205964 cites W2059591371 @default.
- W2057205964 cites W2060372234 @default.
- W2057205964 cites W2062240872 @default.
- W2057205964 cites W2063789470 @default.
- W2057205964 cites W2063852201 @default.
- W2057205964 cites W2065896797 @default.
- W2057205964 cites W2066456560 @default.
- W2057205964 cites W2069277048 @default.
- W2057205964 cites W2069619905 @default.
- W2057205964 cites W2069929255 @default.
- W2057205964 cites W2070755192 @default.
- W2057205964 cites W2071867975 @default.
- W2057205964 cites W2074196937 @default.
- W2057205964 cites W2074629755 @default.
- W2057205964 cites W2075998623 @default.
- W2057205964 cites W2076375535 @default.
- W2057205964 cites W2076516490 @default.
- W2057205964 cites W2077229049 @default.
- W2057205964 cites W2077277355 @default.