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- W2057222145 abstract "1. Hexachlorobenzene induces the cytochtome P-450 system in rat liver microsomes. The catalytic activity of the enzyme towards various substrates (dealkylation of 7-ethoxycoumarin, hydroxylation of biphenyl and NADPH-dependent reduction of cytochrome c) corresponds to that obtained in animals treated with a mixture of phenobarbital and benzpyrene.2. Electrophoretic separation of the partly purified hexachlorobenzene-induced cytochrome P-450 in sodium dodecyl sulphate polyacrylamide gels exhibits a protein pattern similar to that found in microsomes from rats treated with phenobarbital plus benzpyrene." @default.
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- W2057222145 date "1980-01-01" @default.
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- W2057222145 title "Enzymic and electrophoretic characterization of the hexachlorobenzene-induced cytochrome P-450 in the liver of rat" @default.
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- W2057222145 doi "https://doi.org/10.3109/00498258009033740" @default.
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