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- W2057255868 abstract "1. Chromate is taken up by rat thymocytes over a wide range of extracellular chromate concentrations (0˙074 ± 5˙0 mM).2. Chromate uptake followed Michaelis-Menten kinetics and was inhibited by 4-acetamido-4′-isothiocyano-stilbene-2,2′-disulphonic acid, suggesting that the anion carrier was responsible for the uptake by rat thymocytes.3. The decrease in chromate uptake by the thiol(SH)-blocking agent diethyl maleate, the increased chromate uptake caused by the thiol-protecting agent dithiothreitol, and the reduction of glutathione/glutathione disulphide ratio indicated that the maintenance of the integrity of SH-groups greatly influenced the uptake and reduction of Cr(VI), and that glutathione may be responsible for the intracellular reduction of Cr(VI) to Cr(III)." @default.
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- W2057255868 date "1988-01-01" @default.
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- W2057255868 title "Uptake of chromate by rat thymocytes and role of glutathione in its cytoplasmic reduction" @default.
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- W2057255868 doi "https://doi.org/10.3109/00498258809041704" @default.
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