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• W2057267677 abstract "Receptor–ligand interactions are fundamental to the regulation of cell physiology, enabling the communication between cells and their environment via signal transduction. Receptors are also exploited by toxins and infectious agents to mediate pathogenesis. Over the past 20 years, however, this bi-partite paradigm for cellular regulation, that is, receptors and their ligands, has been revised to include an unforeseen participant namely, soluble receptors or molecular decoys. Decoys function as nature's modifiers of potent responses such as inflammation, stimulation of cell proliferation and triggering apoptosis. Decoys not only provide the means to fine tune the regulation of these phenomena; they also serve as potential leads for the development of recombinant anti-toxins, anti-viral agents and novel therapeutics for combating cancer and inflammatory disease." @default.
• W2057267677 created "2016-06-24" @default.
• W2057267677 creator A5001523592 @default.
• W2057267677 date "2008-12-01" @default.
• W2057267677 modified "2023-09-26" @default.
• W2057267677 title "Molecular decoys: antidotes, therapeutics and immunomodulators" @default.
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• W2057267677 doi "https://doi.org/10.1016/j.copbio.2008.10.001" @default.
• W2057267677 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7127390" @default.
• W2057267677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18977299" @default.
• W2057267677 hasPublicationYear "2008" @default.
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