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- W2057268636 abstract "MAINTENANCE OF MICROCIRCULATORY PERFUSION and oxygenation is a prerequisite for preservation of organ function. Studies in the nineties demonstrated gastric mucosal pH, which reflects the level of microcirculatory oxygenation, was clinically diagnostic for the level of disease severity in critically ill patients. 1 Maynard N. Bihari D. Beale R. et al. Assessment of splanchnic oxygenation by gastric tonometry in patients with acute circulatory failure. JAMA. 1993; 270: 1203-1210 Crossref PubMed Scopus (371) Google Scholar , 2 Dantzker D.R. The gastrointestinal tract. The canary of the body?. JAMA. 1993; 270: 1247-1248 Crossref PubMed Scopus (150) Google Scholar This pathophysiologic concept was adopted in many studies focusing on acute and chronic microcirculatory derangements in the intensive care setting. 3 Spronk P.E. Zandstra D.F. Ince C. Bench-to-bedside review: Sepsis is a disease of the microcirculation. Crit Care. 2004; 8: 462-468 Crossref PubMed Scopus (222) Google Scholar The acknowledgement of microcirculatory perfusion derangements as part of the pathophysiology underlying sepsis has led to extension of microcirculation studies to the cardiac surgical setting, as this may reflect the impact of anesthesia, surgery, and cardiovascular complications on patient outcome. 4 Vellinga N.A. Ince C. Boerma E.C. Microvascular dysfunction in the surgical patient. Curr Opin Crit Care. 2010; 16: 377-383 Crossref PubMed Scopus (19) Google Scholar , 5 Den Uil C.A. Lagrand W.K. van der Ent M. et al. Impaired microcirculation predicts poor outcome of patients with acute myocardial infarction complicated by cardiogenic shock. Eur Heart J. 2010; 31: 3032-3039 Crossref PubMed Scopus (146) Google Scholar" @default.
- W2057268636 created "2016-06-24" @default.
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- W2057268636 date "2014-10-01" @default.
- W2057268636 modified "2023-09-27" @default.
- W2057268636 title "Changes in Microcirculatory Perfusion and Oxygenation During Cardiac Surgery With or Without Cardiopulmonary Bypass" @default.
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- W2057268636 doi "https://doi.org/10.1053/j.jvca.2013.04.009" @default.
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