FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057298051> ?p ?o ?g. }

• W2057298051 endingPage "55" @default.
• W2057298051 startingPage "48" @default.
• W2057298051 abstract "<h3>Objective:</h3> To detect automatically focal cortical dysplasia (FCD) type II in patients with extratemporal epilepsy initially diagnosed as MRI-negative on routine inspection of 1.5 and 3.0T scans. <h3>Methods:</h3> We implemented an automated classifier relying on surface-based features of FCD morphology and intensity, taking advantage of their covariance. The method was tested on 19 patients (15 with histologically confirmed FCD) scanned at 3.0T, and cross-validated using a leave-one-out strategy. We assessed specificity in 24 healthy controls and 11 disease controls with temporal lobe epilepsy. Cross-dataset classification performance was evaluated in 20 healthy controls and 14 patients with histologically verified FCD examined at 1.5T. <h3>Results:</h3> Sensitivity was 74%, with 100% specificity (i.e., no lesions detected in healthy or disease controls). In 50% of cases, a single cluster colocalized with the FCD lesion, while in the remaining cases a median of 1 extralesional cluster was found. Applying the classifier (trained on 3.0T data) to the 1.5T dataset yielded comparable performance (sensitivity 71%, specificity 95%). <h3>Conclusion:</h3> In patients initially diagnosed as MRI-negative, our fully automated multivariate approach offered a substantial gain in sensitivity over standard radiologic assessment. The proposed method showed generalizability across cohorts, scanners, and field strengths. Machine learning may assist presurgical decision-making by facilitating hypothesis formulation about the epileptogenic zone. <h3>Classification of evidence:</h3> This study provides Class II evidence that automated machine learning of MRI patterns accurately identifies FCD among patients with extratemporal epilepsy initially diagnosed as MRI-negative." @default.
• W2057298051 created "2016-06-24" @default.
• W2057298051 creator A5005096130 @default.
• W2057298051 creator A5017878656 @default.
• W2057298051 creator A5018674074 @default.
• W2057298051 creator A5035326417 @default.
• W2057298051 creator A5075090194 @default.
• W2057298051 date "2014-06-04" @default.
• W2057298051 modified "2023-10-16" @default.
• W2057298051 title "Automated detection of cortical dysplasia type II in MRI-negative epilepsy" @default.
• W2057298051 cites W1506281249 @default.
• W2057298051 cites W1545396860 @default.
• W2057298051 cites W1586522120 @default.
• W2057298051 cites W1965321448 @default.
• W2057298051 cites W1973903858 @default.
• W2057298051 cites W1991894653 @default.
• W2057298051 cites W1999468553 @default.
• W2057298051 cites W2004371395 @default.
• W2057298051 cites W2011842664 @default.
• W2057298051 cites W2021225636 @default.
• W2057298051 cites W2029241968 @default.
• W2057298051 cites W2031191642 @default.
• W2057298051 cites W2040203353 @default.
• W2057298051 cites W2058046532 @default.
• W2057298051 cites W2060712151 @default.
• W2057298051 cites W2062502470 @default.
• W2057298051 cites W2067471959 @default.
• W2057298051 cites W2069816479 @default.
• W2057298051 cites W2070424142 @default.
• W2057298051 cites W2072021035 @default.
• W2057298051 cites W2072499064 @default.
• W2057298051 cites W2074904157 @default.
• W2057298051 cites W2095512333 @default.
• W2057298051 cites W2105727230 @default.
• W2057298051 cites W2111875400 @default.
• W2057298051 cites W2119603520 @default.
• W2057298051 cites W2129021600 @default.
• W2057298051 cites W2131339155 @default.
• W2057298051 cites W2138304538 @default.
• W2057298051 cites W2139925805 @default.
• W2057298051 cites W2141796362 @default.
• W2057298051 cites W2143514443 @default.
• W2057298051 cites W2144007430 @default.
• W2057298051 cites W2151765069 @default.
• W2057298051 cites W2153295642 @default.
• W2057298051 cites W2157848968 @default.
• W2057298051 cites W2158035368 @default.
• W2057298051 cites W2160609984 @default.
• W2057298051 cites W2164930173 @default.
• W2057298051 cites W2799061466 @default.
• W2057298051 doi "https://doi.org/10.1212/wnl.0000000000000543" @default.
• W2057298051 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4114179" @default.
• W2057298051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24898923" @default.
• W2057298051 hasPublicationYear "2014" @default.
• W2057298051 type Work @default.
• W2057298051 sameAs 2057298051 @default.
• W2057298051 citedByCount "137" @default.
• W2057298051 countsByYear W20572980512012 @default.
• W2057298051 countsByYear W20572980512014 @default.
• W2057298051 countsByYear W20572980512015 @default.
• W2057298051 countsByYear W20572980512016 @default.
• W2057298051 countsByYear W20572980512017 @default.
• W2057298051 countsByYear W20572980512018 @default.
• W2057298051 countsByYear W20572980512019 @default.
• W2057298051 countsByYear W20572980512020 @default.
• W2057298051 countsByYear W20572980512021 @default.
• W2057298051 countsByYear W20572980512022 @default.
• W2057298051 countsByYear W20572980512023 @default.
• W2057298051 crossrefType "journal-article" @default.
• W2057298051 hasAuthorship W2057298051A5005096130 @default.
• W2057298051 hasAuthorship W2057298051A5017878656 @default.
• W2057298051 hasAuthorship W2057298051A5018674074 @default.
• W2057298051 hasAuthorship W2057298051A5035326417 @default.
• W2057298051 hasAuthorship W2057298051A5075090194 @default.
• W2057298051 hasBestOaLocation W20572980512 @default.
• W2057298051 hasConcept C118552586 @default.
• W2057298051 hasConcept C126838900 @default.
• W2057298051 hasConcept C138496976 @default.
• W2057298051 hasConcept C143409427 @default.
• W2057298051 hasConcept C15744967 @default.
• W2057298051 hasConcept C27158222 @default.
• W2057298051 hasConcept C2777060296 @default.
• W2057298051 hasConcept C2778186239 @default.
• W2057298051 hasConcept C2781099131 @default.
• W2057298051 hasConcept C71924100 @default.
• W2057298051 hasConceptScore W2057298051C118552586 @default.
• W2057298051 hasConceptScore W2057298051C126838900 @default.
• W2057298051 hasConceptScore W2057298051C138496976 @default.
• W2057298051 hasConceptScore W2057298051C143409427 @default.
• W2057298051 hasConceptScore W2057298051C15744967 @default.
• W2057298051 hasConceptScore W2057298051C27158222 @default.
• W2057298051 hasConceptScore W2057298051C2777060296 @default.
• W2057298051 hasConceptScore W2057298051C2778186239 @default.
• W2057298051 hasConceptScore W2057298051C2781099131 @default.
• W2057298051 hasConceptScore W2057298051C71924100 @default.
• W2057298051 hasIssue "1" @default.
• W2057298051 hasLocation W20572980511 @default.
• W2057298051 hasLocation W20572980512 @default.

• next