FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057303709> ?p ?o ?g. }

• W2057303709 endingPage "379" @default.
• W2057303709 startingPage "373" @default.
• W2057303709 abstract "Abstract Polybrominated diphenylethers (PBDEs) are widely used as flame retardants. Significant amounts of PBDEs are present in the milk of lactating women. The possible neurotoxic effects of PBDEs are not well known. Perinatal exposure to PBDEs affects both motor and cognitive functions by mechanisms that remain unclear. Some types of learning depend on N ‐methyl‐ d ‐aspartate receptor activation, which increases intracellular calcium that binds to calmodulin and activates nitric oxide synthase, increasing nitric oxide formation that activates guanylate cyclase, increasing cGMP formation. Part of this cGMP is released to the extracellular fluid. We studied whether prenatal exposure of rats to PBDE99 alters the function of this glutamate–nitric oxide–cGMP pathway in rat brain in vivo . At 10 weeks of age, rats treated with PBDE99 showed increased function of the glutamate–nitric oxide–cGMP pathway in brain in vivo , as assessed by microdialysis in freely moving rats. The increased function of the pathway was reproduced in primary cultures of cerebellar neurons prepared from rats prenatally exposed to PBDE99 as well as in neurons cultured from normal rats and treated in vitro with PBDE99. Increased calmodulin content and activation of soluble guanylate cyclase by nitric oxide contributed to the increased function of the pathway." @default.
• W2057303709 created "2016-06-24" @default.
• W2057303709 creator A5021628048 @default.
• W2057303709 creator A5046081761 @default.
• W2057303709 creator A5062390725 @default.
• W2057303709 creator A5070740276 @default.
• W2057303709 creator A5083471906 @default.
• W2057303709 date "2007-01-01" @default.
• W2057303709 modified "2023-10-16" @default.
• W2057303709 title "Prenatal exposure to polybrominated diphenylether 99 enhances the function of the glutamate?nitric oxide?cGMP pathway in brain in�vivo and in cultured neurons" @default.
• W2057303709 cites W1971425761 @default.
• W2057303709 cites W1973788688 @default.
• W2057303709 cites W1986820923 @default.
• W2057303709 cites W1995514535 @default.
• W2057303709 cites W2000843849 @default.
• W2057303709 cites W2005082521 @default.
• W2057303709 cites W2010325396 @default.
• W2057303709 cites W2015944836 @default.
• W2057303709 cites W2043422509 @default.
• W2057303709 cites W2064437259 @default.
• W2057303709 cites W2074641481 @default.
• W2057303709 cites W2075472484 @default.
• W2057303709 cites W2076158001 @default.
• W2057303709 cites W2083306186 @default.
• W2057303709 cites W2092908224 @default.
• W2057303709 cites W2093851147 @default.
• W2057303709 cites W2112480342 @default.
• W2057303709 cites W2114041290 @default.
• W2057303709 cites W2147618435 @default.
• W2057303709 cites W2155249159 @default.
• W2057303709 cites W2172022460 @default.
• W2057303709 doi "https://doi.org/10.1111/j.1460-9568.2006.05289.x" @default.
• W2057303709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17284177" @default.
• W2057303709 hasPublicationYear "2007" @default.
• W2057303709 type Work @default.
• W2057303709 sameAs 2057303709 @default.
• W2057303709 citedByCount "28" @default.
• W2057303709 countsByYear W20573037092012 @default.
• W2057303709 countsByYear W20573037092013 @default.
• W2057303709 countsByYear W20573037092014 @default.
• W2057303709 countsByYear W20573037092015 @default.
• W2057303709 countsByYear W20573037092016 @default.
• W2057303709 countsByYear W20573037092017 @default.
• W2057303709 countsByYear W20573037092018 @default.
• W2057303709 countsByYear W20573037092020 @default.
• W2057303709 countsByYear W20573037092021 @default.
• W2057303709 crossrefType "journal-article" @default.
• W2057303709 hasAuthorship W2057303709A5021628048 @default.
• W2057303709 hasAuthorship W2057303709A5046081761 @default.
• W2057303709 hasAuthorship W2057303709A5062390725 @default.
• W2057303709 hasAuthorship W2057303709A5070740276 @default.
• W2057303709 hasAuthorship W2057303709A5083471906 @default.
• W2057303709 hasConcept C126322002 @default.
• W2057303709 hasConcept C134018914 @default.
• W2057303709 hasConcept C150903083 @default.
• W2057303709 hasConcept C170493617 @default.
• W2057303709 hasConcept C181199279 @default.
• W2057303709 hasConcept C185592680 @default.
• W2057303709 hasConcept C207001950 @default.
• W2057303709 hasConcept C2777622882 @default.
• W2057303709 hasConcept C28406088 @default.
• W2057303709 hasConcept C29688787 @default.
• W2057303709 hasConcept C50156730 @default.
• W2057303709 hasConcept C519581460 @default.
• W2057303709 hasConcept C55493867 @default.
• W2057303709 hasConcept C61174792 @default.
• W2057303709 hasConcept C71924100 @default.
• W2057303709 hasConcept C79879829 @default.
• W2057303709 hasConcept C86803240 @default.
• W2057303709 hasConceptScore W2057303709C126322002 @default.
• W2057303709 hasConceptScore W2057303709C134018914 @default.
• W2057303709 hasConceptScore W2057303709C150903083 @default.
• W2057303709 hasConceptScore W2057303709C170493617 @default.
• W2057303709 hasConceptScore W2057303709C181199279 @default.
• W2057303709 hasConceptScore W2057303709C185592680 @default.
• W2057303709 hasConceptScore W2057303709C207001950 @default.
• W2057303709 hasConceptScore W2057303709C2777622882 @default.
• W2057303709 hasConceptScore W2057303709C28406088 @default.
• W2057303709 hasConceptScore W2057303709C29688787 @default.
• W2057303709 hasConceptScore W2057303709C50156730 @default.
• W2057303709 hasConceptScore W2057303709C519581460 @default.
• W2057303709 hasConceptScore W2057303709C55493867 @default.
• W2057303709 hasConceptScore W2057303709C61174792 @default.
• W2057303709 hasConceptScore W2057303709C71924100 @default.
• W2057303709 hasConceptScore W2057303709C79879829 @default.
• W2057303709 hasConceptScore W2057303709C86803240 @default.
• W2057303709 hasIssue "2" @default.
• W2057303709 hasLocation W20573037091 @default.
• W2057303709 hasLocation W20573037092 @default.
• W2057303709 hasOpenAccess W2057303709 @default.
• W2057303709 hasPrimaryLocation W20573037091 @default.
• W2057303709 hasRelatedWork W1833184044 @default.
• W2057303709 hasRelatedWork W1968730502 @default.
• W2057303709 hasRelatedWork W1971106099 @default.
• W2057303709 hasRelatedWork W1994090017 @default.
• W2057303709 hasRelatedWork W2011932585 @default.
• W2057303709 hasRelatedWork W2039914241 @default.
• W2057303709 hasRelatedWork W2074474806 @default.

• next