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- W2057307552 abstract "<b>Background:</b> Inhalers mishandling remains common in real-life and is associated with poor clinical control. <b>Aims and Objectives:</b> This study aimed to compare different inhalers handling by chronic obstructive pulmonary disease (COPD) patients with no past-experience. <b>Methods:</b> In this open-label, cross-over study, 180 COPD patients were randomized to handle 10 placebo inhalers including pressurized metered dose inhaler (pMDI), Aerolizer, Handihaler, Turbohaler, Diskus, Breezhaler, Ellipta, Easyhaler, Diskhaler and Respimat without receiving any instructions. Inhalers with a reported past-experience were excluded. The correct use of the inhaler was then demonstrated and patient was reevaluated. Demonstration was repeated till a complete right handling. Total correct handling steps and number of counseling attempts were recorded. <b>Results:</b> Mean±SD percentages of total correct steps were 50.08±18.70, 52.13±15.80, 57.89±14.38, 59.52±17.46, 63.54±10.36, 66.98±15.96, 71.87±17.36, 73.33±11.46, 77.08±13.82 and 85.95±11.42% for Respimat, pMDI, Diskhaler, Diskus, Aerolizer, Handihaler, Easyhaler, Turbohaler, Breezhaler and Ellipta respectively with p<0.001. Ellipta showed the highest percentage of participants with a complete right handling with no counseling (20%) and with one counseling attempt (77.78%). On the other hand, Diskhaler, pMDI and Respimat were the only inhalers included in a forth counseling attempt. <b>Conclusion:</b> Inhalers greatly vary in their ease of use ranging from easy inhalers like Ellipta to intermediate inhalers like Easyhaler and Handihaler followed by difficult inhalers like pMDI and Respimat which necessitates repeated counseling when prescribing inhalers for the first time." @default.
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- W2057307552 date "2001-11-17" @default.
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- W2057307552 title "Accuracy of a single question in screening for depression in a cohort of patients after stroke: comparative study" @default.
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- W2057307552 doi "https://doi.org/10.1136/bmj.323.7322.1159" @default.
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