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- W2057308728 abstract "Wound healing comprises four distinct phases and involves many cell events and biologic markers. The use of nanoparticles for topical application has gaining attention due to its deeper penetration in the skin and the retention capacity of the drug in the site of application. In this study the effect and toxicity of mucoadhesive polymeric nanoparticles loaded with enoxaparin was evaluated in in vivo model of skin ulcer. Our results showed an interesting formulation based on mucoadhesive nanoparticles with enoxaparin that improved wound healing without cytotoxicity in vitro in all endpoint evaluated. Then, this semi-solid formulation is a promising option for skin ulcer treatment." @default.
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- W2057308728 date "2013-04-10" @default.
- W2057308728 modified "2023-10-03" @default.
- W2057308728 title "In vivotoxicity of enoxaparin encapsulated in mucoadhesive nanoparticles: Topical application in a wound healing model" @default.
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- W2057308728 doi "https://doi.org/10.1088/1742-6596/429/1/012031" @default.
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