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- W2057308974 abstract "Craniofacial skeletal muscles (CskM), including the masticatory (MM), extraocular (EOM) and laryngeal muscles (LM), have a number of properties that set them apart from the majority of skeletal muscles (SkM). They have embryological origins that are distinct from musculature elsewhere in the body, they express a number of immature myosin heavy chain isoforms and maintain increased and distinct expression of a number of myogenic growth factors and their receptors from other adult SkMs. Furthermore, it has recently been demonstrated that unlike limb SkM, normal adult EOM and LM retain a population of activated satellite cells, the regenerative cell in adult SkM. In order to maintain this proliferative pool throughout life, CSkM may contain more satellite cells and/or more multipotent precursor cells that may be more resistant to apoptosis than those found in limb muscle. A further exciting question is whether this potentially more active muscle precursor cell population could be utilized not only for SkM repair, but be harnessed for repair or reconstruction of other tissues, such as nervous tissue or bone. This is a highly attractive speculation as the innate regenerative capacity of craniofacial muscles would ensure the donor tissue would not have compromised future function." @default.
- W2057308974 created "2016-06-24" @default.
- W2057308974 creator A5010002142 @default.
- W2057308974 creator A5044353895 @default.
- W2057308974 creator A5057066902 @default.
- W2057308974 creator A5062701994 @default.
- W2057308974 date "2007-02-13" @default.
- W2057308974 modified "2023-10-14" @default.
- W2057308974 title "Myogenic precursor cells in craniofacial muscles" @default.
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- W2057308974 doi "https://doi.org/10.1111/j.1601-0825.2006.01353.x" @default.
- W2057308974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17305613" @default.
- W2057308974 hasPublicationYear "2007" @default.
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