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• W2057315057 endingPage "31673" @default.
• W2057315057 startingPage "31666" @default.
• W2057315057 abstract "Increases in intracellular free Ca2+ play a major role in many cellular processes. The deregulation of Ca2+ signaling is a feature of a variety of diseases, and modulators of Ca2+ signaling are used to treat conditions as diverse as hypertension to pain. The Ca2+ signal also plays a role in processes important in cancer, such as proliferation and migration. Many studies in cancer have identified alterations in the expression of proteins involved in the movement of Ca2+ across the plasma membrane and subcellular organelles. In some cases, these Ca2+ channels or pumps are potential therapeutic targets for specific cancer subtypes or correlate with prognosis. Increases in intracellular free Ca2+ play a major role in many cellular processes. The deregulation of Ca2+ signaling is a feature of a variety of diseases, and modulators of Ca2+ signaling are used to treat conditions as diverse as hypertension to pain. The Ca2+ signal also plays a role in processes important in cancer, such as proliferation and migration. Many studies in cancer have identified alterations in the expression of proteins involved in the movement of Ca2+ across the plasma membrane and subcellular organelles. In some cases, these Ca2+ channels or pumps are potential therapeutic targets for specific cancer subtypes or correlate with prognosis." @default.
• W2057315057 created "2016-06-24" @default.
• W2057315057 creator A5035468956 @default.
• W2057315057 creator A5087186958 @default.
• W2057315057 creator A5087976195 @default.
• W2057315057 date "2012-09-01" @default.
• W2057315057 modified "2023-10-11" @default.
• W2057315057 title "Calcium Channels and Pumps in Cancer: Changes and Consequences" @default.
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