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• W2057327534 abstract "Observations are reported on the blood platelet 5‐hydroxytryptamine content of six patients receiving imipramine, N ‐(γ‐dimethylaminopropyl)‐iminodibenzyl hydrochloride. The response was a fall to a level of one‐sixth of the original in three weeks, with little change thereafter. This is in sharp contrast to the action of iproniazid which caused a rise of some 200% in the blood platelet 5‐hydroxytryptamine level over the same period. Imipramine in a concentration of 1 mg./ml. had no inhibitory action on 5‐hydroxytryptophan decarboxylase; 8·0 μg./ml. of imipramine suppressed two‐thirds of the in vitro uptake of 5‐hydroxytryptamine (2·5 μg./ml.) by normal human platelets." @default.
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• W2057327534 date "1960-03-01" @default.
• W2057327534 modified "2023-10-13" @default.
• W2057327534 title "THE EFFECT OF IPRONIAZID AND IMIPRAMINE ON THE BLOOD PLATELET 5-HYDROXYTRYPTAMINE LEVEL IN MAN" @default.
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• W2057327534 doi "https://doi.org/10.1111/j.1476-5381.1960.tb01207.x" @default.
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