Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057339218> ?p ?o ?g. }
- W2057339218 abstract "Thrombotic microangiopathy (TMA) is a rare but devastating small vessels disorder that is characterized by intravascular platelet thrombi, thrombocytopenia, and various degrees of organ ischemia and anemia, which is due to erythrocyte fragmentation in microcirculation.The Aim of this study was to determine the von Willebrand factor-cleaving protease (ADAMTS13) activity during the acute phase of TMA. We also investigated inhibiting antibodies against ADAMTS13 in these patients.In a collaborative work with Mario-Negro institute of pharmacological research in Bergamo-Italy, we registered the clinical and laboratory data, collected the serum samples, and transferred the samples to the laboratories. Serum samples were taken before the start of plasmapheresis or at least 15 days after the final exchange.We recruited 40 patients (14 males and 26 females) with the mean age of 46.12 ± 17.26 years. The mean activity of ADAMTS13 was 34.58% ± 21.83%. Two patients had inhibitory antibodies against ADAMTS13 with profound deficiency of ADAMTS13 activity (< 6%). Infectious diseases were the most common underlying condition, followed by systemic lupus erythematous.Majority of patients had an underlying condition and had various ADAMTS13 activity. The presence of inhibiting antibodies and accompanied complete deficiency of ADAMTS13 activity is an indicator of severity." @default.
- W2057339218 created "2016-06-24" @default.
- W2057339218 creator A5067537047 @default.
- W2057339218 creator A5074779124 @default.
- W2057339218 date "2014-11-11" @default.
- W2057339218 modified "2023-10-16" @default.
- W2057339218 title "Von Willebrand Factor-Cleaving Protease Activity in Thrombotic Microangiopathy: First Report From Iran" @default.
- W2057339218 cites W1491802934 @default.
- W2057339218 cites W1592666461 @default.
- W2057339218 cites W1976309553 @default.
- W2057339218 cites W1998334483 @default.
- W2057339218 cites W2032471106 @default.
- W2057339218 cites W2035667239 @default.
- W2057339218 cites W2056427896 @default.
- W2057339218 cites W2064910821 @default.
- W2057339218 cites W2065410181 @default.
- W2057339218 cites W2072324749 @default.
- W2057339218 cites W2078417703 @default.
- W2057339218 cites W2096735552 @default.
- W2057339218 cites W2096868979 @default.
- W2057339218 cites W2098937235 @default.
- W2057339218 cites W2101061562 @default.
- W2057339218 cites W2105979263 @default.
- W2057339218 cites W2114979410 @default.
- W2057339218 cites W2115642465 @default.
- W2057339218 cites W2121848782 @default.
- W2057339218 cites W2128011986 @default.
- W2057339218 cites W2145422492 @default.
- W2057339218 cites W2147073846 @default.
- W2057339218 cites W2151503986 @default.
- W2057339218 cites W2155933413 @default.
- W2057339218 cites W2159055433 @default.
- W2057339218 cites W2315229770 @default.
- W2057339218 cites W2340760838 @default.
- W2057339218 cites W4238378618 @default.
- W2057339218 cites W4294829823 @default.
- W2057339218 cites W91483767 @default.
- W2057339218 doi "https://doi.org/10.5812/numonthly.18900" @default.
- W2057339218 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4330667" @default.
- W2057339218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25738110" @default.
- W2057339218 hasPublicationYear "2014" @default.
- W2057339218 type Work @default.
- W2057339218 sameAs 2057339218 @default.
- W2057339218 citedByCount "1" @default.
- W2057339218 countsByYear W20573392182021 @default.
- W2057339218 crossrefType "journal-article" @default.
- W2057339218 hasAuthorship W2057339218A5067537047 @default.
- W2057339218 hasAuthorship W2057339218A5074779124 @default.
- W2057339218 hasBestOaLocation W20573392181 @default.
- W2057339218 hasConcept C126322002 @default.
- W2057339218 hasConcept C134018914 @default.
- W2057339218 hasConcept C159654299 @default.
- W2057339218 hasConcept C203014093 @default.
- W2057339218 hasConcept C2776513394 @default.
- W2057339218 hasConcept C2777878052 @default.
- W2057339218 hasConcept C2778585876 @default.
- W2057339218 hasConcept C2778842783 @default.
- W2057339218 hasConcept C2779134260 @default.
- W2057339218 hasConcept C2779394231 @default.
- W2057339218 hasConcept C2780921031 @default.
- W2057339218 hasConcept C555293320 @default.
- W2057339218 hasConcept C71924100 @default.
- W2057339218 hasConcept C89560881 @default.
- W2057339218 hasConcept C90924648 @default.
- W2057339218 hasConceptScore W2057339218C126322002 @default.
- W2057339218 hasConceptScore W2057339218C134018914 @default.
- W2057339218 hasConceptScore W2057339218C159654299 @default.
- W2057339218 hasConceptScore W2057339218C203014093 @default.
- W2057339218 hasConceptScore W2057339218C2776513394 @default.
- W2057339218 hasConceptScore W2057339218C2777878052 @default.
- W2057339218 hasConceptScore W2057339218C2778585876 @default.
- W2057339218 hasConceptScore W2057339218C2778842783 @default.
- W2057339218 hasConceptScore W2057339218C2779134260 @default.
- W2057339218 hasConceptScore W2057339218C2779394231 @default.
- W2057339218 hasConceptScore W2057339218C2780921031 @default.
- W2057339218 hasConceptScore W2057339218C555293320 @default.
- W2057339218 hasConceptScore W2057339218C71924100 @default.
- W2057339218 hasConceptScore W2057339218C89560881 @default.
- W2057339218 hasConceptScore W2057339218C90924648 @default.
- W2057339218 hasIssue "6" @default.
- W2057339218 hasLocation W20573392181 @default.
- W2057339218 hasLocation W20573392182 @default.
- W2057339218 hasLocation W20573392183 @default.
- W2057339218 hasLocation W20573392184 @default.
- W2057339218 hasOpenAccess W2057339218 @default.
- W2057339218 hasPrimaryLocation W20573392181 @default.
- W2057339218 hasRelatedWork W2002452949 @default.
- W2057339218 hasRelatedWork W2057339218 @default.
- W2057339218 hasRelatedWork W2066825159 @default.
- W2057339218 hasRelatedWork W2075323718 @default.
- W2057339218 hasRelatedWork W2084620947 @default.
- W2057339218 hasRelatedWork W2092127489 @default.
- W2057339218 hasRelatedWork W2158730091 @default.
- W2057339218 hasRelatedWork W2799279069 @default.
- W2057339218 hasRelatedWork W4226423976 @default.
- W2057339218 hasRelatedWork W589665374 @default.
- W2057339218 hasVolume "6" @default.
- W2057339218 isParatext "false" @default.
- W2057339218 isRetracted "false" @default.
- W2057339218 magId "2057339218" @default.