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- W2057349258 abstract "Abstract The objective of this study was to determine the effect of season on the histologic and histomorphometric appearance of the normal equine pituitary gland. Pituitary glands were collected at necropsy from 121 horses throughout the year. Plasma was also collected from 59 of these horses before euthanasia. Hematoxylin and eosin stained median sagittal sections of each pituitary were evaluated and histologically graded by three pathologists. Histomorphometric analysis was performed on the same slides. Plasma α-melanocyte stimulating hormone was measured by radioimmunoassay in a subset of horses (n = 59). A total of 118 pituitary glands were included in the study after exclusions were made on the basis of the presence of pars intermedia (PI) adenomas (>5 mm). There was a positive correlation between PI hormone concentration (α-melanocyte stimulating hormone) and PI area. Pituitary gland measurements and grades from samples collected in the fall were compared with those collected in the nonfall months using t -test. The PI area, total pituitary area, and PI/total pituitary ratio were significantly greater in the fall compared with nonfall months ( P P P P" @default.
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- W2057349258 date "2012-02-01" @default.
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- W2057349258 title "The Effect of Season on the Histologic and Histomorphometric Appearance of the Equine Pituitary Gland" @default.
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- W2057349258 doi "https://doi.org/10.1016/j.jevs.2011.01.003" @default.
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