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• W2057370324 abstract "The adenine/cytosine1166 (A/C1166) polymorphism of the angiotensin-II type 1 receptor (AGTR1) gene is presumed to be associated with mitral valve prolapse syndrome (MVPS) in Caucasians. To investigate whether a similar association exists among the Chinese population in Taiwan, 100 patients with MVP diagnosed by echocardiography and 100 normal subjects were studied by polymerase chain reaction-based restriction analysis. The difference in genotype (chi2=0.24; p=0.89) and allelic (Yates' chi2=0.06; p=0.81) frequencies between the groups were not significant. Further categorization of the MVP patients into mild and severe subgroups also revealed no statistical difference from the controls. It was concluded that A/C1166 polymorphism of the AGTR1 gene is not a suitable genetic marker of MVPS in Taiwan Chinese." @default.
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• W2057370324 date "2002-01-01" @default.
• W2057370324 modified "2023-10-04" @default.
• W2057370324 title "Angiotensin II Type 1 Receptor Gene Adenine/Cytosine1166 Polymorphism is not Associated With Mitral Valve Prolapse Syndrome in Taiwan Chinese" @default.
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• W2057370324 doi "https://doi.org/10.1253/circj.66.163" @default.
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