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- W2057377231 abstract "The noninvasive, nonradioactive, quantitative nature of magnetic resonance techniques has propelled them to the forefront of neuroscience and neuropsychiatric research. In particular, recent advances have confirmed their enormous potential in patients with Alzheimer disease (AD). Structural and functional magnetic resonance (MR) imaging have demonstrated significant correlation with clinical outcomes and underlying pathology and are used increasingly in the AD clinic. This review will highlight the role of high-resolution structural MR imaging and functional magnetic resonance imaging in the identification of atrophic and hemodynamic changes in AD and their potential as diagnostic biomarkers and surrogates of therapeutic response. Advanced MR techniques based on diffusion, perfusion, and neurochemical abnormalities in the aging brain will be presented briefly. These newer techniques continue to expand our understanding of neuropathology in the aging brain and are likely to play an important clinical role in the future." @default.
- W2057377231 created "2016-06-24" @default.
- W2057377231 creator A5036624449 @default.
- W2057377231 creator A5040631126 @default.
- W2057377231 creator A5090031553 @default.
- W2057377231 date "2005-12-01" @default.
- W2057377231 modified "2023-09-26" @default.
- W2057377231 title "Magnetic Resonance Approaches to Brain Aging and Alzheimer Disease-associated Neuropathology" @default.
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