Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057379780> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2057379780 endingPage "372" @default.
- W2057379780 startingPage "356" @default.
- W2057379780 abstract "The molecular weight calculated from the variance of the gaussian distribution of DNA molecules at equilibrium in a CsCl density gradient appears to be one-half the best estimates of the true molecular weight. This is true for unbroken DNA molecules from T2, T4, T5, P22 and T7 bacteriophages. It follows that, when this factor is taken into account, the calculated molecular weight is a good measure of actual molecular weight for unbroken genetically uniform molecules. This uniform proportionality between calculated molecular weight and the best estimates of the true molecular weight suggests that there is no detectable density heterogeneity in these unbroken molecules, or that there is a contribution by density heterogeneity which increases precisely as 1/M for these molecules of different origins. This is a rather special requirement which renders this alternative unlikely. Shear-produced fragments of T2 DNA give broader bands than would be expected on the basis of whole molecules of comparable size. The calculated molecular weights of these fragments are approximately one-fourth the best estimates of the true molecular weights. It turns out that the observations are just what one would expect if some of the fragments were slightly richer in GC than others. The magnitude of this compositional heterogeneity, its dependence on fragment size and its possible significance are discussed. The formaldehyde-stabilized polynucleotide chains produced by denaturing the fragments have band-width molecular weights which are two-thirds those of the fragments from which they were derived. This is exactly what would be expected if the two chains of the duplex had the same density and the molecular weight is halved when the duplex fragment is denatured and separated into polynucleotide chains." @default.
- W2057379780 created "2016-06-24" @default.
- W2057379780 creator A5034369343 @default.
- W2057379780 creator A5043778328 @default.
- W2057379780 date "1962-09-01" @default.
- W2057379780 modified "2023-09-27" @default.
- W2057379780 title "Sedimentation equilibrium studies on intact and fragmented bacteriophage DNA" @default.
- W2057379780 cites W121683030 @default.
- W2057379780 cites W1975518861 @default.
- W2057379780 cites W1985267130 @default.
- W2057379780 cites W1985810986 @default.
- W2057379780 cites W1998773721 @default.
- W2057379780 cites W2013645958 @default.
- W2057379780 cites W2020497105 @default.
- W2057379780 cites W2029674471 @default.
- W2057379780 cites W2032901228 @default.
- W2057379780 cites W2047976365 @default.
- W2057379780 cites W2055092944 @default.
- W2057379780 cites W2055688420 @default.
- W2057379780 cites W2077479837 @default.
- W2057379780 cites W2085936765 @default.
- W2057379780 cites W2088860002 @default.
- W2057379780 cites W2095283555 @default.
- W2057379780 cites W2110276 @default.
- W2057379780 cites W2403241400 @default.
- W2057379780 doi "https://doi.org/10.1016/s0022-2836(62)80078-3" @default.
- W2057379780 hasPublicationYear "1962" @default.
- W2057379780 type Work @default.
- W2057379780 sameAs 2057379780 @default.
- W2057379780 citedByCount "52" @default.
- W2057379780 crossrefType "journal-article" @default.
- W2057379780 hasAuthorship W2057379780A5034369343 @default.
- W2057379780 hasAuthorship W2057379780A5043778328 @default.
- W2057379780 hasConcept C111921641 @default.
- W2057379780 hasConcept C121332964 @default.
- W2057379780 hasConcept C147597530 @default.
- W2057379780 hasConcept C163716315 @default.
- W2057379780 hasConcept C178790620 @default.
- W2057379780 hasConcept C181199279 @default.
- W2057379780 hasConcept C185592680 @default.
- W2057379780 hasConcept C2778892434 @default.
- W2057379780 hasConcept C32909587 @default.
- W2057379780 hasConcept C43617362 @default.
- W2057379780 hasConcept C46749446 @default.
- W2057379780 hasConcept C54689828 @default.
- W2057379780 hasConcept C552990157 @default.
- W2057379780 hasConcept C55493867 @default.
- W2057379780 hasConcept C58121356 @default.
- W2057379780 hasConcept C62520636 @default.
- W2057379780 hasConceptScore W2057379780C111921641 @default.
- W2057379780 hasConceptScore W2057379780C121332964 @default.
- W2057379780 hasConceptScore W2057379780C147597530 @default.
- W2057379780 hasConceptScore W2057379780C163716315 @default.
- W2057379780 hasConceptScore W2057379780C178790620 @default.
- W2057379780 hasConceptScore W2057379780C181199279 @default.
- W2057379780 hasConceptScore W2057379780C185592680 @default.
- W2057379780 hasConceptScore W2057379780C2778892434 @default.
- W2057379780 hasConceptScore W2057379780C32909587 @default.
- W2057379780 hasConceptScore W2057379780C43617362 @default.
- W2057379780 hasConceptScore W2057379780C46749446 @default.
- W2057379780 hasConceptScore W2057379780C54689828 @default.
- W2057379780 hasConceptScore W2057379780C552990157 @default.
- W2057379780 hasConceptScore W2057379780C55493867 @default.
- W2057379780 hasConceptScore W2057379780C58121356 @default.
- W2057379780 hasConceptScore W2057379780C62520636 @default.
- W2057379780 hasIssue "3" @default.
- W2057379780 hasLocation W20573797801 @default.
- W2057379780 hasOpenAccess W2057379780 @default.
- W2057379780 hasPrimaryLocation W20573797801 @default.
- W2057379780 hasRelatedWork W124195011 @default.
- W2057379780 hasRelatedWork W1517199377 @default.
- W2057379780 hasRelatedWork W1542067355 @default.
- W2057379780 hasRelatedWork W1542159180 @default.
- W2057379780 hasRelatedWork W1563565864 @default.
- W2057379780 hasRelatedWork W1575341303 @default.
- W2057379780 hasRelatedWork W1985234264 @default.
- W2057379780 hasRelatedWork W2084735130 @default.
- W2057379780 hasRelatedWork W2315771994 @default.
- W2057379780 hasRelatedWork W2395635096 @default.
- W2057379780 hasVolume "5" @default.
- W2057379780 isParatext "false" @default.
- W2057379780 isRetracted "false" @default.
- W2057379780 magId "2057379780" @default.
- W2057379780 workType "article" @default.