Matches in SemOpenAlex for { <https://semopenalex.org/work/W205738320> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W205738320 endingPage "7" @default.
- W205738320 startingPage "194" @default.
- W205738320 abstract "The NESTROFT method (Naked Eye Single Tube Red Cell Osmotic Fragility Test) was evaluated against a high performance liquid chromatographic (HPLC) method for its usefulness in screening for beta-thalassaemia and some of the common haemoglobinopathies. Blood samples (137) from patients with suspected haemoglobin disorders were analyzed by both methods. Among the 63 patients with heterozygous beta-thalassaemia on HPLC, NESTROFT was positive for 49, 'doubtful' for 13 and negative for 1. Of the 32 patients with other haemoglobin disorders, 28 were positive on NESTROFT and 4 were 'doubtful'. Of the 42 'normal' samples, NESTROFT was positive for 6, 'doubtful' for 8 and negative for 28. This test showed an overall sensitivity of 98.7 per cent, specificity of 66.6 per cent, positive predictive value of 87 per cent and negative predictive value of 96.5 per cent. We conclude that, NESTROFT is a suitable test for screening for beta-thalassaemia and the common haemoglobinopathies seen in India. It is easy to perform, simple, inexpensive and does not require sophisticated equipment. Subjects who are NESTROFT 'positive' or 'doubtful' deserve further investigation." @default.
- W205738320 created "2016-06-24" @default.
- W205738320 creator A5020662053 @default.
- W205738320 creator A5032393853 @default.
- W205738320 creator A5059298967 @default.
- W205738320 creator A5088428439 @default.
- W205738320 creator A5091640477 @default.
- W205738320 date "1996-08-01" @default.
- W205738320 modified "2023-09-23" @default.
- W205738320 title "NESTROFT as a screening test for the detection of thalassaemia & common haemoglobinopathies--an evaluation against a high performance liquid chromatographic method." @default.
- W205738320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8840659" @default.
- W205738320 hasPublicationYear "1996" @default.
- W205738320 type Work @default.
- W205738320 sameAs 205738320 @default.
- W205738320 citedByCount "15" @default.
- W205738320 countsByYear W2057383202012 @default.
- W205738320 countsByYear W2057383202013 @default.
- W205738320 countsByYear W2057383202014 @default.
- W205738320 countsByYear W2057383202017 @default.
- W205738320 countsByYear W2057383202018 @default.
- W205738320 countsByYear W2057383202021 @default.
- W205738320 crossrefType "journal-article" @default.
- W205738320 hasAuthorship W205738320A5020662053 @default.
- W205738320 hasAuthorship W205738320A5032393853 @default.
- W205738320 hasAuthorship W205738320A5059298967 @default.
- W205738320 hasAuthorship W205738320A5088428439 @default.
- W205738320 hasAuthorship W205738320A5091640477 @default.
- W205738320 hasConcept C126322002 @default.
- W205738320 hasConcept C147509754 @default.
- W205738320 hasConcept C187212893 @default.
- W205738320 hasConcept C2779902561 @default.
- W205738320 hasConcept C3019719930 @default.
- W205738320 hasConcept C3020067899 @default.
- W205738320 hasConcept C71924100 @default.
- W205738320 hasConcept C90924648 @default.
- W205738320 hasConceptScore W205738320C126322002 @default.
- W205738320 hasConceptScore W205738320C147509754 @default.
- W205738320 hasConceptScore W205738320C187212893 @default.
- W205738320 hasConceptScore W205738320C2779902561 @default.
- W205738320 hasConceptScore W205738320C3019719930 @default.
- W205738320 hasConceptScore W205738320C3020067899 @default.
- W205738320 hasConceptScore W205738320C71924100 @default.
- W205738320 hasConceptScore W205738320C90924648 @default.
- W205738320 hasLocation W2057383201 @default.
- W205738320 hasOpenAccess W205738320 @default.
- W205738320 hasPrimaryLocation W2057383201 @default.
- W205738320 hasRelatedWork W1501950790 @default.
- W205738320 hasRelatedWork W2046024352 @default.
- W205738320 hasRelatedWork W2055781229 @default.
- W205738320 hasRelatedWork W205738320 @default.
- W205738320 hasRelatedWork W2095306786 @default.
- W205738320 hasRelatedWork W2145213465 @default.
- W205738320 hasRelatedWork W2189200885 @default.
- W205738320 hasRelatedWork W2402727783 @default.
- W205738320 hasRelatedWork W2405302437 @default.
- W205738320 hasRelatedWork W2417209194 @default.
- W205738320 hasVolume "104" @default.
- W205738320 isParatext "false" @default.
- W205738320 isRetracted "false" @default.
- W205738320 magId "205738320" @default.
- W205738320 workType "article" @default.