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• W2057404767 abstract "The ageing of the population in Western countries and the wide use of modern techniques of neuroimaging has led to an increased finding of benign intracranial tumours, namely meningiomas, in the elderly. 1 Helseth A The incidence of primary central nervous system neoplasms before and after computerized tomography availability. J Neurosurg. 1995; 83: 999-1003 Crossref PubMed Scopus (69) Google Scholar These slow-growing tumours, often with few symptoms, may prevent these patients from leading an autonomous life. 2 Rengachary SS Suskind DL Meningiomas in the elderly and asymptomatic meningiomas. in: Al-Mefty Meningiomas. Raven Press, New York1991: 153-159 Google Scholar To assess the impact of surgery on quality of life, we studied 37 patients aged over 75 years, who were operated upon between 1992 and 1996 in three institutions. The patients included ten men and 27 women; their mean age was 77·5 years (range 75–84); 21 tumours were larger than 4 cm, 16 were smaller. Total removal was achieved in 31 and subtotal in six. Meningioma locations were: convexity (22), anterior cranial fossa (six), posterior cranial fossa (four), falx (three), middle cranial fossa (one), and sphenocavernous (one). The patients' general condition was evaluated according to the American Society of Anesthesiology (ASA) 3 Schneider AJL Assessment of risk factors and surgical outcome. Surg Clin North Am. 1983; 63: 113-119 Google Scholar : six were grade I, 21 II, and ten III. Patients graded IV were not considered for surgery. Their neurological conditions were related to the Karnofsky Performance Scale (KPS). 4 Karnofky DA Abelmann WH Craver LF Burchenal JH The use of the nitrogen mustards in the palliative treatment of carcinoma, with particular reference to bronchogenic carcinoma. Cancer. 1948; 1: 634-656 Crossref Scopus (1855) Google Scholar We assumed that a KPS score of 70 or more was acceptable, as the patients would be at least able to care for themselves at home. 25 patients scored 70 or more preoperatively, 12 less. All the patients were studied by computed tomography or magnetic resonance imaging, or both. Tumour size and peritumourous oedema were evaluated as hypothetical prognostic factors. The results were evaluated upon discharge and after 6 months, a period that was arbitrarily assumed as sufficient for neurological recovery. The differences between preoperative KPS (KPS 0), discharge KPS (KPS 1), and follow-up KPS (KPS 2) were computed and matched with the Wilcoxon paired test to assess the impact of the following factors on outcome: tumour location and size, peritumourous oedema, ASA grading, and preoperative neurological conditions. 2 Rengachary SS Suskind DL Meningiomas in the elderly and asymptomatic meningiomas. in: Al-Mefty Meningiomas. Raven Press, New York1991: 153-159 Google Scholar , 5 Cornu Ph Chatellier G Dagreou F et al. Intracranial meningiomas in elderly patients: postoperative morbidity and mortality. Factors predictive of outcome. Acta Neurochir (Wien). 1990; 102: 98-102 Crossref PubMed Scopus (85) Google Scholar DEPARTMENT OF ERROREpidemic ciprofloxacin-resistant Salmonella typhi in Tajikistan—In this research letter by D A Murdoch and colleagues (Jan 31, p 339), the correct name of the second author is N Banatvala. Full-Text PDF" @default.
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• W2057404767 title "Is surgery useful in very old patients with intracranial meningioma?" @default.
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• W2057404767 doi "https://doi.org/10.1016/s0140-6736(98)24005-0" @default.
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