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- W2057414063 startingPage "171" @default.
- W2057414063 abstract "Tinea capitis is perhaps the most common mycotic infection in children. In North America the epidemiology of tinea capitis has changed so that now predominates over . With this transition the utility of the Wood's light for diagnosis has been reduced since infection is Wood's light negative. Griseofulvin has been the mainstay of therapy for the last 40 years. The newer antifungal agents—itraconazole, terbinafine, and fluconazole—appear to be effective and safe for the treatment of tinea capitis. When tinea capitis is due to or other endothrix species the following regimens have been used: itraconazole continuous regimen (5 mg/kg/day for 4 weeks), itraconazole pulse regimen with capsules (5 mg/kg/day for 1 week plus 1–3 pulses 3 weeks apart), and itraconazole pulse regimen with oral solution (3 mg/kg/day for 1 week plus 1–3 pulses 3 weeks apart). With terbinafine tablets the continuous regimen (>40 kg body weight, 250 mg/day; 20–40 kg, 125 mg/day; and <20 kg, 125 mg/day) is given for 2 to 4 weeks. Fluconazole tablets or oral suspension (6 mg/kg/day) were administered for 20 days in one trial. Another possibility may be 6 mg/kg/day for 2 weeks and evaluating the scalp 4 weeks later. An extra week of therapy (6 mg/kg/day) can be administered if clinically indicated at that time. A once‐weekly regimen may also be effective. When ectothrix organisms (e.g., ) are present, a longer duration of therapy may be required. The data suggest that the newer agents are effective, safe with few adverse effects, and have a high benefit:risk ratio. It remains to be seen to what extent griseofulvin will be superseded for the treatment of tinea capitis. Adjunctive therapies may help decrease the risk of infection to other individuals. Appropriate measures should be taken to reduce the possibility of reinfection." @default.
- W2057414063 created "2016-06-24" @default.
- W2057414063 creator A5001854931 @default.
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- W2057414063 date "1999-05-01" @default.
- W2057414063 modified "2023-10-18" @default.
- W2057414063 title "Tinea Capitis: An Overview with Emphasis on Management" @default.
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