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• W2057421785 abstract "Modification of the St. John's wort acylphloroglucinol constituent, hyperforin (1), by acylation, alkylation, and oxidation resulted in detrimental effects on the inhibition of the synaptosomal accumulation of serotonin, showing the existence of definite structure-activity relationships in this in vitro test system and highlighting the role of the enolized cyclohexanedione moiety for activity on neurotransmitter reuptake." @default.
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• W2057421785 date "2002-03-22" @default.
• W2057421785 modified "2023-10-06" @default.
• W2057421785 title "Synthesis and Biological Evaluation of Hyperforin Analogues. Part I. Modification of the Enolized Cyclohexanedione Moiety" @default.
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• W2057421785 doi "https://doi.org/10.1021/np0105681" @default.
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