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- W2057427465 abstract "Abstract Changes in segmentally mediated sympathetic reactions and lower extremity flexor responses to repetitive afferent stimulation of a peripheral nerve were studied in 9 patients with a functionally complete transection of the cervical spinal cord. The sympathetic reactions were recorded in terms of skin conductance responses from the palms, and the flexor responses were monitored in terms of the integrated EMG activity of the tibialis anterior muscle. The stimuli were comprised of pulse trains applied percutaneously to the posterior tibial nerve of the limb from which the EMG was recorded. The same intensity was used for the series of repetitive stimuli and for the test stimuli which preceded and followed repetitive stimulation. The manner in which both the sympathetic and flexor reactions were affected by different rates and by different numbers of stimuli was consistent with the parametric characteristics which have been ascribed to the habituation process. For both modalities of responses, repetitive stimulation at the rate of 120/min resulted in a much greater decrement of responding to test stimuli than did stimulation at the rate of 12/min. When the number of stimuli at the rate of 120/min was reduced from 360 to 90, the magnitude of responses to test stimuli was less depressed and the rate of spontaneous recovery was faster. The recovery rate of both skin conductance responses and flexor EMG activity was progressively slowed by applying successive series of 120/min repetitive stimuli, separated by sets of test stimuli. The influence of effector fatigue in accounting for the effects of repetitive stimulation was investigated by applying test stimuli to two different sites, only one of which was submitted to prolonged repetitive stimulation. Both for skin conductance responses and flexor EMG activity, the only responses to decrease in magnitude were those elicited from the site which had been stimulated repetitively. Similarities in the habituation of sympathetic and flexor reactions were considered from the standpoint of reflex pathway components which the two systems share." @default.
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- W2057427465 date "1972-07-01" @default.
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- W2057427465 title "Habituation of skin conductance responses and flexor withdrawal activity mediated by the functionally transected human spinal cord" @default.
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- W2057427465 doi "https://doi.org/10.1016/0006-8993(72)90536-7" @default.
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