FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057452495> ?p ?o ?g. }

• W2057452495 endingPage "15" @default.
• W2057452495 startingPage "9" @default.
• W2057452495 abstract "Urokinase-type plasminogen activator (u-PA) occurs either in a single-chain form or in a two chain form (scu-PA or tcu-PA, respectively). The occurrence of the different forms of u-PA and the formation of u-PA-inhibitor complexes was studied in urine samples from 10 healthy donors. Measurement by means of a bio-immunoassay showed that the urine samples contained 307±189ng/ml u-PA (mean±SD), of which 72±15% occurred in the active two chain form and 28±15% in the plasmin-activatable single chain form. SDS-polyacrylamide gel electrophoresis followed by fibrin zymography revealed that fresh urine contained no, or only traces of, u-PA-inhibitor complexes. In contrast to what has previously been published, the bulk of u-PA appeared to be in an uncomplexed 55 kD form. Incubation of urine at 37°C for 8 h did not lead to the formation of u-PA-inhibitor complexes. However, after rapid removal of the low molecular weight fraction of urine on a gel filtration column a 100kD complex, consisting of u-PA and plasminogen activator inhibitor-3/protein C inhibitor, was formed during incubation (t1/2≈45 min). Complex formation was dependent on stimulation by urinary glycosaminoglycans and only occurred at a low ionic strength, which explains why no complexes were formed in the untreated urine samples of healthy donors." @default.
• W2057452495 created "2016-06-24" @default.
• W2057452495 creator A5019194869 @default.
• W2057452495 creator A5035254428 @default.
• W2057452495 creator A5067445500 @default.
• W2057452495 creator A5072577339 @default.
• W2057452495 date "1994-01-01" @default.
• W2057452495 modified "2023-10-16" @default.
• W2057452495 title "Urokinase and its complex with plasminogen activator inhibitor-3/protein C inhibitor in urine" @default.
• W2057452495 cites W1497178009 @default.
• W2057452495 cites W1514200453 @default.
• W2057452495 cites W1540618467 @default.
• W2057452495 cites W1547887043 @default.
• W2057452495 cites W1562054825 @default.
• W2057452495 cites W1569894631 @default.
• W2057452495 cites W1604233325 @default.
• W2057452495 cites W1968135936 @default.
• W2057452495 cites W1972728733 @default.
• W2057452495 cites W1975077689 @default.
• W2057452495 cites W1984345973 @default.
• W2057452495 cites W1990002012 @default.
• W2057452495 cites W1996636157 @default.
• W2057452495 cites W1997350055 @default.
• W2057452495 cites W2000512540 @default.
• W2057452495 cites W2001645649 @default.
• W2057452495 cites W2006122994 @default.
• W2057452495 cites W2027025266 @default.
• W2057452495 cites W2044851532 @default.
• W2057452495 cites W2051024238 @default.
• W2057452495 cites W2055465498 @default.
• W2057452495 cites W2057251756 @default.
• W2057452495 cites W2061946617 @default.
• W2057452495 cites W2074554626 @default.
• W2057452495 cites W2085793911 @default.
• W2057452495 cites W2100837269 @default.
• W2057452495 cites W2110222118 @default.
• W2057452495 cites W2398617376 @default.
• W2057452495 cites W2400820400 @default.
• W2057452495 cites W2414256049 @default.
• W2057452495 cites W2414598072 @default.
• W2057452495 cites W2415114669 @default.
• W2057452495 cites W2472015541 @default.
• W2057452495 cites W30895601 @default.
• W2057452495 cites W95127911 @default.
• W2057452495 doi "https://doi.org/10.1016/0268-9499(94)90026-4" @default.
• W2057452495 hasPublicationYear "1994" @default.
• W2057452495 type Work @default.
• W2057452495 sameAs 2057452495 @default.
• W2057452495 citedByCount "2" @default.
• W2057452495 crossrefType "journal-article" @default.
• W2057452495 hasAuthorship W2057452495A5019194869 @default.
• W2057452495 hasAuthorship W2057452495A5035254428 @default.
• W2057452495 hasAuthorship W2057452495A5067445500 @default.
• W2057452495 hasAuthorship W2057452495A5072577339 @default.
• W2057452495 hasConcept C126322002 @default.
• W2057452495 hasConcept C134018914 @default.
• W2057452495 hasConcept C177430391 @default.
• W2057452495 hasConcept C181199279 @default.
• W2057452495 hasConcept C185592680 @default.
• W2057452495 hasConcept C193363816 @default.
• W2057452495 hasConcept C203014093 @default.
• W2057452495 hasConcept C25642318 @default.
• W2057452495 hasConcept C2776892390 @default.
• W2057452495 hasConcept C2779679481 @default.
• W2057452495 hasConcept C2780026642 @default.
• W2057452495 hasConcept C2781071845 @default.
• W2057452495 hasConcept C43617362 @default.
• W2057452495 hasConcept C54173615 @default.
• W2057452495 hasConcept C55493867 @default.
• W2057452495 hasConcept C71924100 @default.
• W2057452495 hasConcept C86803240 @default.
• W2057452495 hasConceptScore W2057452495C126322002 @default.
• W2057452495 hasConceptScore W2057452495C134018914 @default.
• W2057452495 hasConceptScore W2057452495C177430391 @default.
• W2057452495 hasConceptScore W2057452495C181199279 @default.
• W2057452495 hasConceptScore W2057452495C185592680 @default.
• W2057452495 hasConceptScore W2057452495C193363816 @default.
• W2057452495 hasConceptScore W2057452495C203014093 @default.
• W2057452495 hasConceptScore W2057452495C25642318 @default.
• W2057452495 hasConceptScore W2057452495C2776892390 @default.
• W2057452495 hasConceptScore W2057452495C2779679481 @default.
• W2057452495 hasConceptScore W2057452495C2780026642 @default.
• W2057452495 hasConceptScore W2057452495C2781071845 @default.
• W2057452495 hasConceptScore W2057452495C43617362 @default.
• W2057452495 hasConceptScore W2057452495C54173615 @default.
• W2057452495 hasConceptScore W2057452495C55493867 @default.
• W2057452495 hasConceptScore W2057452495C71924100 @default.
• W2057452495 hasConceptScore W2057452495C86803240 @default.
• W2057452495 hasIssue "1" @default.
• W2057452495 hasLocation W20574524951 @default.
• W2057452495 hasOpenAccess W2057452495 @default.
• W2057452495 hasPrimaryLocation W20574524951 @default.
• W2057452495 hasRelatedWork W1978567224 @default.
• W2057452495 hasRelatedWork W2000512540 @default.
• W2057452495 hasRelatedWork W2021156020 @default.
• W2057452495 hasRelatedWork W2042124258 @default.
• W2057452495 hasRelatedWork W2057452495 @default.
• W2057452495 hasRelatedWork W2061946617 @default.

• next