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• W2057462308 abstract "The purpose of this research was to develop and evaluate controlled release matrix tablets of paracetamol based on natural gum exudates of Albizia procera. Procera gum was characterized of its properties like compressibility index, angle of repose, viscosity and moisture content. The interaction between the gum and paracetamol was also studied through differential scanning calorimetry (DSC) and FTIR spectroscopy. Matrix tablets were then prepared by wet granulation method with different concentrations of procera gum and hydroxypropyl methylcellulose (HPMC) and evaluated for their physical properties like weight variation, hardness, friability and content uniformity. Dissolution study was conducted to characterize release mechanism from the matrix system and data were fitted to various kinetic models. The mechanism of drug release from both types of matrix tablets was found to be anomalous type. Results from various evaluations suggested that A. procera gum could be used as drug release retardant in controlled release matrix systems." @default.
• W2057462308 created "2016-06-24" @default.
• W2057462308 creator A5053755306 @default.
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• W2057462308 date "2012-09-01" @default.
• W2057462308 modified "2023-09-27" @default.
• W2057462308 title "Albizia procera gum as an excipient for oral controlled release matrix tablet" @default.
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• W2057462308 doi "https://doi.org/10.1016/j.carbpol.2012.05.038" @default.
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