Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057479546> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2057479546 endingPage "172" @default.
- W2057479546 startingPage "164" @default.
- W2057479546 abstract "The inhibition of dihydropteroate synthase extracts by sulfones and sulfonamides has been determined. Structural dependency of the observed I50-values has been quantitatively explained by multiple regression and principal component analysis. New highly active sulfones have been synthesized guided by the derived QSAR. The analysis leads to the conclusion that electronic and steric substituent effects are decisive and that sulfones and sulfonamides are binding to the same receptor site. The LFE-descriptors used are correlated with the minimal conformational entropy. The results are also compared with the results obtained in cell-free and whole cell systems of bacteria. The additional influence of cell-wall permeability on inhibitory efficacy is demonstrated." @default.
- W2057479546 created "2016-06-24" @default.
- W2057479546 creator A5004265073 @default.
- W2057479546 creator A5034107450 @default.
- W2057479546 creator A5052330076 @default.
- W2057479546 creator A5058202359 @default.
- W2057479546 creator A5081595116 @default.
- W2057479546 creator A5086062840 @default.
- W2057479546 date "1987-01-01" @default.
- W2057479546 modified "2023-10-14" @default.
- W2057479546 title "Multiple Regression Analysis of Antimalarial Activities of Sulfones and Sulfonamides in Cell-Free Systems and Principal Component Analysis to Compare with Antibacterial Activities" @default.
- W2057479546 cites W1970984569 @default.
- W2057479546 cites W1985025849 @default.
- W2057479546 cites W2003470293 @default.
- W2057479546 cites W2016304490 @default.
- W2057479546 cites W2027850078 @default.
- W2057479546 cites W2045931025 @default.
- W2057479546 cites W2046791332 @default.
- W2057479546 cites W2317885510 @default.
- W2057479546 cites W2321391550 @default.
- W2057479546 cites W2328716735 @default.
- W2057479546 cites W4249473000 @default.
- W2057479546 doi "https://doi.org/10.1002/qsar.19870060404" @default.
- W2057479546 hasPublicationYear "1987" @default.
- W2057479546 type Work @default.
- W2057479546 sameAs 2057479546 @default.
- W2057479546 citedByCount "23" @default.
- W2057479546 crossrefType "journal-article" @default.
- W2057479546 hasAuthorship W2057479546A5004265073 @default.
- W2057479546 hasAuthorship W2057479546A5034107450 @default.
- W2057479546 hasAuthorship W2057479546A5052330076 @default.
- W2057479546 hasAuthorship W2057479546A5058202359 @default.
- W2057479546 hasAuthorship W2057479546A5081595116 @default.
- W2057479546 hasAuthorship W2057479546A5086062840 @default.
- W2057479546 hasConcept C105795698 @default.
- W2057479546 hasConcept C115903868 @default.
- W2057479546 hasConcept C164126121 @default.
- W2057479546 hasConcept C185592680 @default.
- W2057479546 hasConcept C19768560 @default.
- W2057479546 hasConcept C201194858 @default.
- W2057479546 hasConcept C203014093 @default.
- W2057479546 hasConcept C27438332 @default.
- W2057479546 hasConcept C2777035104 @default.
- W2057479546 hasConcept C2777234095 @default.
- W2057479546 hasConcept C2778048844 @default.
- W2057479546 hasConcept C2778371730 @default.
- W2057479546 hasConcept C2778689049 @default.
- W2057479546 hasConcept C33923547 @default.
- W2057479546 hasConcept C41008148 @default.
- W2057479546 hasConcept C48921125 @default.
- W2057479546 hasConcept C71240020 @default.
- W2057479546 hasConcept C74887250 @default.
- W2057479546 hasConcept C86803240 @default.
- W2057479546 hasConceptScore W2057479546C105795698 @default.
- W2057479546 hasConceptScore W2057479546C115903868 @default.
- W2057479546 hasConceptScore W2057479546C164126121 @default.
- W2057479546 hasConceptScore W2057479546C185592680 @default.
- W2057479546 hasConceptScore W2057479546C19768560 @default.
- W2057479546 hasConceptScore W2057479546C201194858 @default.
- W2057479546 hasConceptScore W2057479546C203014093 @default.
- W2057479546 hasConceptScore W2057479546C27438332 @default.
- W2057479546 hasConceptScore W2057479546C2777035104 @default.
- W2057479546 hasConceptScore W2057479546C2777234095 @default.
- W2057479546 hasConceptScore W2057479546C2778048844 @default.
- W2057479546 hasConceptScore W2057479546C2778371730 @default.
- W2057479546 hasConceptScore W2057479546C2778689049 @default.
- W2057479546 hasConceptScore W2057479546C33923547 @default.
- W2057479546 hasConceptScore W2057479546C41008148 @default.
- W2057479546 hasConceptScore W2057479546C48921125 @default.
- W2057479546 hasConceptScore W2057479546C71240020 @default.
- W2057479546 hasConceptScore W2057479546C74887250 @default.
- W2057479546 hasConceptScore W2057479546C86803240 @default.
- W2057479546 hasIssue "4" @default.
- W2057479546 hasLocation W20574795461 @default.
- W2057479546 hasOpenAccess W2057479546 @default.
- W2057479546 hasPrimaryLocation W20574795461 @default.
- W2057479546 hasRelatedWork W1591997400 @default.
- W2057479546 hasRelatedWork W163556339 @default.
- W2057479546 hasRelatedWork W2079127050 @default.
- W2057479546 hasRelatedWork W2090042039 @default.
- W2057479546 hasRelatedWork W2097456009 @default.
- W2057479546 hasRelatedWork W2100732429 @default.
- W2057479546 hasRelatedWork W2123041977 @default.
- W2057479546 hasRelatedWork W2324321910 @default.
- W2057479546 hasRelatedWork W2405756818 @default.
- W2057479546 hasRelatedWork W3206784178 @default.
- W2057479546 hasVolume "6" @default.
- W2057479546 isParatext "false" @default.
- W2057479546 isRetracted "false" @default.
- W2057479546 magId "2057479546" @default.
- W2057479546 workType "article" @default.