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- W2057482314 abstract "A previously healthy 65-year-old gentleman with no known allergies developed a diffuse generalized pruritic, exanthematous rash over 24 hours (Fig. 1). Five days before, he had suffered a non-ST-elevation myocardial infarction. His treatment included primary percutaneous coronary intervention with drug-eluting stents and was started on ticagrelor, aspirin, simvastatin, bisoprolol, and ramipril. The temporal relationship, along with a skin biopsy, which revealed perivascular dermatitis with a lymphocytic infiltrate, was consistent with a delayed (type IV) hypersensitivity reaction to a similar P2Y12 inhibitor, clopidogrel (Fig. 1). 1 Cheema A.N. Mohammad A. Hong T. et al. Characterization of clopidogrel hypersensitivity reactions and management with oral steroids without clopidogrel discontinuation. J Am Coll Cardiol. 2011; 58: 1445-1454 Abstract Full Text Full Text PDF PubMed Scopus (45) Google Scholar" @default.
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- W2057482314 date "2014-08-01" @default.
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- W2057482314 title "First Report of Hypersensitivity to Ticagrelor" @default.
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- W2057482314 doi "https://doi.org/10.1016/j.cjca.2014.04.011" @default.
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