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• W2057486871 abstract "A strategy of systematically targeting more rigid analogues of the known MCH R1 receptor antagonist, SB-568849, serendipitously uncovered a binding mode accessible to N-aryl-phthalimide ligands. Optimisation to improve the stability of this compound class led to the discovery of novel N-aryl-quinazolinones, benzotriazinones and thienopyrimidinones as selective ligands with good affinity for human melanin-concentrating hormone receptor 1." @default.
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• W2057486871 date "2006-09-01" @default.
• W2057486871 modified "2023-10-11" @default.
• W2057486871 title "Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849" @default.
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• W2057486871 doi "https://doi.org/10.1016/j.bmcl.2006.06.061" @default.
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