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• W2057510010 abstract "cDNA cloning of the ?-aminobutyric acid (GABA)(A) receptor ?-subunit from human brain has been attempted in order to clarify its structure. Using a bovine cDNA fragment as a homologous probe, the cDNA clone containing complete coding regions of the GABA(A) receptor ?-subunit was isolated by screening the human brain cDNA library, and its full amino acid sequences were deduced from the nucleotide sequence. The nucleotide and deduced amino acid sequences showed a high homology in comparison with those in bovine brain. The human brain mRNA indicated the presence of a single mRNA species of about 4500 bases by RNA blot hybridization. In addition, Southern blot analysis suggested that the human gene of the GABA(A) receptor ?-subunit might possess an exon-intron organization." @default.
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• W2057510010 date "1989-01-01" @default.
• W2057510010 modified "2023-10-16" @default.
• W2057510010 title "Nucleotide and deduced amino acid sequences of the GABAA receptor α-subunit from human brain" @default.
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• W2057510010 doi "https://doi.org/10.1016/0197-0186(89)90073-9" @default.
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