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- W2057518014 abstract "Guine pigs were made dependent to morphine by a daily s.c. injection of morphine hydrochloride. Half of them were given morphine hydrochloride (50 mg/kg) s.c. 30 min befor sacrifice; these animals were termed ‘morphine-treated’ guinea pigs. The animals in the abstinence syndrome were sacrificed 30 to 40 hr after the last morphine dose. Effective concentrations of 5-hydroxytryptmine on Auerbach's plexus of the guinea pig in the abstinence syndrome was significantly smaller than those on Auerbach's plexus of normal and morphine-treated animals, while the responses to nicotine and caerulein were unchanged. The results suggest that withdrawal of morphine excites the M-receptors in Auerbach's plexus." @default.
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- W2057518014 date "1974-07-01" @default.
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- W2057518014 title "Action of 5-hydroxytryptamine on electrical activity of auerbach's plexus in the ileum of the morphine dependent guinea pig" @default.
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- W2057518014 doi "https://doi.org/10.1016/0014-2999(74)90154-x" @default.
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