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- W2057536080 abstract "Abstract Liver calciferol 25-hydroxylase activity of vitamin-D deficient rats was enhanced 24 hours following the intravenous injection of N 6 -2′-O-dibutyryl adenosine 3′,5′-monophosphate. Sodium butyrate administered in the same way had no effect on this enzyme system. Administration of actinomycin D with N 6 -2′-O-dibutyryl adenosine 3′,5′-monophosphate abolished the stimulatory effect of the cyclic nucleotide. Direct addition to the incubation medium of adenosine 3′,5′-cyclic monophosphate or of its dibutyryl derivative did not influence the hepatic conversion of cholecalciferol to 25-hydroxycholecalciferol. These results suggest a possible role for the cyclic nucleotide in the regulation of this enzyme system." @default.
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- W2057536080 date "1976-08-01" @default.
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- W2057536080 title "The effect of N6-2′-O-dibutyryl-adenosine 3′,5′-monophosphate on rat liver calciferol 25-hydroxylase" @default.
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- W2057536080 doi "https://doi.org/10.1016/0006-291x(76)90764-6" @default.
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