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• W2057579672 abstract "Peroxisomes are apparently missing in Zellweger syndrome; nevertheless, some of the integral membrane proteins of the organelle are present. Their distribution was studied by immunofluorescence microscopy. In control fibroblasts, peroxisomes appeared as small dots. In Zellweger fibroblasts, the peroxisomal membrane proteins were located in unusual empty membrane structures of larger size. These results suggest that the primary defect in this disease may be in the mechanism for import of matrix proteins." @default.
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• W2057579672 date "1988-03-25" @default.
• W2057579672 modified "2023-10-03" @default.
• W2057579672 title "Peroxisomal Membrane Ghosts in Zellweger Syndrome—Aberrant Organelle Assembly" @default.
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• W2057579672 doi "https://doi.org/10.1126/science.3281254" @default.
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