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- W2057584345 abstract "Treatment of children and adolescents with juvenile idiopathic arthritis and other pediatric rheumatic diseases has evolved. Where once there was only a limited arsenal of medications, with significant side effects and inadequate efficacy, today, with an increased understanding of the pathogenesis of these diseases, there is a wider variety of more targeted and effective treatments. TNF-α is a cytokine involved in a number of inflammatory pathways in pediatric rheumatic diseases. The emergence of biologic modifiers that target TNF-α has been pivotal in providing the ability to deliver early and aggressive treatment. Adalimumab, a recombinant monoclonal antibody to TNF-α, is an important therapeutic option, which affords children and adolescents with chronic illnesses an improved quality of life." @default.
- W2057584345 created "2016-06-24" @default.
- W2057584345 creator A5036066851 @default.
- W2057584345 date "2012-06-01" @default.
- W2057584345 modified "2023-09-26" @default.
- W2057584345 title "Role of adalimumab in the management of children and adolescents with juvenile idiopathic arthritis and other rheumatic conditions" @default.
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- W2057584345 doi "https://doi.org/10.2147/ahmt.s22607" @default.
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