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- W2057604111 abstract "Abstract The action of ionic strength on the esterasic activity of trypsin (EC 3.4.4.4) has been investigated with specific substrates. A substantial effect of ionic strength on the ionisation p K of the histidine located at the active center is observed. The shift of this p K is explained by a repulsive interaction between the charged imidazole group and two positive charges. Some comparative experiments carried out with acetyltrypsin led to the identification of these charges as the e -NH 3 + of two lysine residues." @default.
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- W2057604111 date "1968-01-01" @default.
- W2057604111 modified "2023-09-27" @default.
- W2057604111 title "Influence de la force ionique sur l'activite de la trypsine et de la trypsine acetylee" @default.
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- W2057604111 doi "https://doi.org/10.1016/0005-2744(68)90171-x" @default.
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