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- W2057608384 abstract "The new lactosyl donor 8, bearing an Fmoc-protected hydroxy group, has been prepared from lactose for the solid-phase synthesis of lactose-containing oligosaccharides. In addition to the preparation of 3b-O-fucosyllactoside 1 (with donor 4), use of this new building block has permitted the syntheses of 3b-O-mannosyllactoside 2 and of human milk oligosaccharide lacto-N-tetraoside 3, with known donors 5 and 6, respectively. These successful, high-yielding syntheses demonstrate the usefulness of Fmoc-protected O-glycosyl trichloroacetimidate 8 for the solid-phase construction of oligosaccharides, by an ester-type linker strategy." @default.
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- W2057608384 date "2001-06-01" @default.
- W2057608384 modified "2023-10-14" @default.
- W2057608384 title "Solid-Phase Synthesis of Lactose-Containing Oligosaccharides" @default.
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- W2057608384 doi "https://doi.org/10.1002/1099-0690(200106)2001:11<2067::aid-ejoc2067>3.0.co;2-9" @default.
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