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- W2057625089 abstract "Human natural killer (NK) cells are built to kill abnormal cells but to preserve autologous normal cells. To accomplish this task, they are equipped with a large number of inhibiting and activating receptors. Ligation with corresponding ligands will determine whether the NK cell becomes activated to destroy the abnormal cell. This review will focus on the abnormalities of NK cell receptors and their putative ligands found in patients with leukemia, which can lead to an inadequate function of NK cells allowing these malignant cells to escape from NK cell destruction. In recent years it has become clear that NK cells in the haploidentical hematopoietic stem cell transplantation (HSCT) setting are very effective in eliminating residual acute myeloid, but not acute lymphoid, leukemic cells. In this regard, we also reviewed published studies of retrospective cohorts of HSCT investigating the potential beneficial effect of killer-cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) ligands on NK alloreactivity. Manipulating NK cell inhibition or activation could lead to new forms of immunotherapy, ultimately leading to the elimination of resistant leukemic cells." @default.
- W2057625089 created "2016-06-24" @default.
- W2057625089 creator A5004750881 @default.
- W2057625089 creator A5054623834 @default.
- W2057625089 date "2007-11-29" @default.
- W2057625089 modified "2023-10-15" @default.
- W2057625089 title "NK cell receptors and their ligands in leukemia" @default.
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- W2057625089 cites W1580335186 @default.
- W2057625089 cites W160233928 @default.
- W2057625089 cites W1942967920 @default.
- W2057625089 cites W1963647603 @default.
- W2057625089 cites W1964671991 @default.
- W2057625089 cites W1964982854 @default.
- W2057625089 cites W1966103694 @default.
- W2057625089 cites W1969961365 @default.
- W2057625089 cites W1974323215 @default.
- W2057625089 cites W1977778943 @default.
- W2057625089 cites W1977992597 @default.
- W2057625089 cites W1981967635 @default.
- W2057625089 cites W1988916255 @default.
- W2057625089 cites W1989712520 @default.
- W2057625089 cites W1991672921 @default.
- W2057625089 cites W1997565001 @default.
- W2057625089 cites W2005837456 @default.
- W2057625089 cites W2008693616 @default.
- W2057625089 cites W2008992933 @default.
- W2057625089 cites W2013053106 @default.
- W2057625089 cites W2014349052 @default.
- W2057625089 cites W2015054607 @default.
- W2057625089 cites W2016200146 @default.
- W2057625089 cites W2018492618 @default.
- W2057625089 cites W2019932788 @default.
- W2057625089 cites W2019958642 @default.
- W2057625089 cites W2027626832 @default.
- W2057625089 cites W2029667797 @default.
- W2057625089 cites W2033938501 @default.
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- W2057625089 cites W2037189240 @default.
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- W2057625089 cites W2038832277 @default.
- W2057625089 cites W2044435667 @default.
- W2057625089 cites W2044835282 @default.
- W2057625089 cites W2045422742 @default.
- W2057625089 cites W2052336384 @default.
- W2057625089 cites W2052502668 @default.
- W2057625089 cites W2053402248 @default.
- W2057625089 cites W2057781614 @default.
- W2057625089 cites W2058949406 @default.
- W2057625089 cites W2062733828 @default.
- W2057625089 cites W2064008845 @default.
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- W2057625089 cites W2073643201 @default.
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- W2057625089 cites W2079241332 @default.
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- W2057625089 cites W2084483244 @default.
- W2057625089 cites W2085478834 @default.
- W2057625089 cites W2087576224 @default.
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- W2057625089 cites W2131282129 @default.
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- W2057625089 cites W2147068163 @default.
- W2057625089 cites W2152859298 @default.
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- W2057625089 doi "https://doi.org/10.1038/sj.leu.2405040" @default.
- W2057625089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18046448" @default.
- W2057625089 hasPublicationYear "2007" @default.
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