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- W2057671715 abstract "Sister-chromatid exchanges (SCEs) in a permanent cell line of human lymphoblastoid cells were induced by 3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]-indole (Trp-P-1), 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyldipyridol[1,2-a:3′,2′-d]imidazole (Glu-P-1) and 2-amino-9H-pyrido[2,3-b]indole (2-amino-α-carboline). The first two compounds were found in tryptophan pyrolysates, the third in a glutamic acid pyrolysate and the last in a globulin pyrolysate. All these compounds required the metabolic activation system (S9 mix) for induction of SCE. Trp-P-2 had the highest SCE-inducing activity of these chemicals (approximately equivalent to that of aflatoxin B1), followed by Trp-P-1, Glu-P-1 and then 2-amino-α-carboline." @default.
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- W2057671715 date "1984-10-01" @default.
- W2057671715 modified "2023-09-26" @default.
- W2057671715 title "Examination of DNA lesion by the alkaline elution technique. II. DNA lesion induced by hydrogen peroxide" @default.
- W2057671715 doi "https://doi.org/10.1016/0165-1161(84)90037-2" @default.
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