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- W2057687436 abstract "Highly differentiated, spontaneous hepatomas occurring in 13- to 15-month-old CBA mice were unable to produce embryo-specific serum protein alpha-fetoprotein (AFP). AFP synthesis, however, was induced in such tumors by minimal mechanical damage (small incisions of the tumors). On the 3rd day following surgery, AFP-positive cells were detected in two zones: (1) along the inflammatory shaft arising around the peripheral parts of incisions, and (2) near large blood vessels draining the damaged areas. It is suggested that mechanisms regulating AFP synthesis in highly differentiated hepatomas are similar to those of the normal liver and are related to local structural rearrangements." @default.
- W2057687436 created "2016-06-24" @default.
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- W2057687436 date "1985-01-15" @default.
- W2057687436 modified "2023-09-23" @default.
- W2057687436 title "AFP-synthesis induction in mouse hepatomas" @default.
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- W2057687436 doi "https://doi.org/10.1002/ijc.2910350121" @default.
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