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- W2057690405 abstract "In this study, we report a facile method for the preparation of core–shell magnetic molecularly imprinted polymers (MIPs) for protein recognition. Uniform carboxyl group functionalized Fe3O4 nanoparticles (NPs) were synthesized using a solvothermal method. Magnetic MIPs were synthesized by self-polymerization of dopamine in the presence of template protein on the surface of the Fe3O4 NPs. A thin layer of polydopamine can be coated on Fe3O4 NPs via dopamine self-polymerization and the imprinted polydopamine shells can be controlled by the mass ratio of Fe3O4 NPs and dopamine. More importantly, there is a critical value of polydopamine shell thickness for the maximum rebinding capacity. The as-prepared lysozyme-imprinted Fe3O4@polydopamine NPs show high binding capacity and acceptable specific recognition behavior towards template proteins. This method provides the possibility for the separation and enrichment of abundant proteins in proteomic analysis." @default.
- W2057690405 created "2016-06-24" @default.
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- W2057690405 date "2012-01-01" @default.
- W2057690405 modified "2023-10-15" @default.
- W2057690405 title "A self-assembled polydopamine film on the surface of magnetic nanoparticles for specific capture of protein" @default.
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- W2057690405 doi "https://doi.org/10.1039/c2nr30316g" @default.
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