FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057706738> ?p ?o ?g. }

• W2057706738 endingPage "8292" @default.
• W2057706738 startingPage "8280" @default.
• W2057706738 abstract "Adipocyte differentiation and the extent of subsequent fat accumulation are closely related to the occurrence and progression of diseases such as insulin resistance and obesity. Black soybean koji (BSK) is produced by the fermentation of black soybean with Aspergilllus awamori. Previous study indicated that BSK extract has antioxidative and multifunctional bioactivities, however, the role of BSK in the regulation of energy metabolism is still unclear. We aimed to investigate the effect of glucose utilization on insulin-resistant 3T3-L1 preadipocytes and adipogenesis-related protein expression in differentiated adipocytes with BSK treatment. Cytoxicity assay revealed that BSK did not adversely affect cell viability at levels up to 200 µg/mL. The potential for glucose utilization was increased by increased glucose transporter 1 (GLUT1), GLUT4 and protein kinase B (AKT) protein expression in insulin-resistant 3T3-L1 cells in response to BSK treatment. Simultaneously, BSK inhibited lipid droplet accumulation in differentiated 3T3-L1 cells. The inhibitory effect of adipogenesis was associated with downregulated peroxisome proliferator-activated receptor g (PPARγ) level and upregulated Acrp30 protein expression. Our results suggest that BSK extract could improve glucose uptake by modulating GLUT1 and GLUT4 expression in a 3T3-L1 insulin-resistance cell model. In addition, BSK suppressed differentiation and lipid accumulation in mature 3T3-L1 adipocytes, which may suggest its potential for food supplementation to prevent obesity and related metabolic abnormalities." @default.
• W2057706738 created "2016-06-24" @default.
• W2057706738 creator A5008950331 @default.
• W2057706738 creator A5017949708 @default.
• W2057706738 creator A5021264677 @default.
• W2057706738 creator A5055184323 @default.
• W2057706738 creator A5084875777 @default.
• W2057706738 date "2014-05-09" @default.
• W2057706738 modified "2023-10-17" @default.
• W2057706738 title "Effect of Black Soybean Koji Extract on Glucose Utilization and Adipocyte Differentiation in 3T3-L1 Cells" @default.
• W2057706738 cites W1488559297 @default.
• W2057706738 cites W1524321743 @default.
• W2057706738 cites W1587875569 @default.
• W2057706738 cites W1967013117 @default.
• W2057706738 cites W1967490916 @default.
• W2057706738 cites W1972175193 @default.
• W2057706738 cites W1974802955 @default.
• W2057706738 cites W1984064393 @default.
• W2057706738 cites W1984600798 @default.
• W2057706738 cites W1990912522 @default.
• W2057706738 cites W2006548992 @default.
• W2057706738 cites W2021152731 @default.
• W2057706738 cites W2030610437 @default.
• W2057706738 cites W2032375016 @default.
• W2057706738 cites W2040640228 @default.
• W2057706738 cites W2053519480 @default.
• W2057706738 cites W2054628430 @default.
• W2057706738 cites W2064904173 @default.
• W2057706738 cites W2069497802 @default.
• W2057706738 cites W2071915296 @default.
• W2057706738 cites W2076957803 @default.
• W2057706738 cites W2080128757 @default.
• W2057706738 cites W2080493811 @default.
• W2057706738 cites W2097511872 @default.
• W2057706738 cites W2104698958 @default.
• W2057706738 cites W2119911216 @default.
• W2057706738 cites W2122144826 @default.
• W2057706738 cites W2124991668 @default.
• W2057706738 cites W2132549912 @default.
• W2057706738 cites W2143642040 @default.
• W2057706738 doi "https://doi.org/10.3390/ijms15058280" @default.
• W2057706738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4057731" @default.
• W2057706738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24821545" @default.
• W2057706738 hasPublicationYear "2014" @default.
• W2057706738 type Work @default.
• W2057706738 sameAs 2057706738 @default.
• W2057706738 citedByCount "15" @default.
• W2057706738 countsByYear W20577067382015 @default.
• W2057706738 countsByYear W20577067382017 @default.
• W2057706738 countsByYear W20577067382018 @default.
• W2057706738 countsByYear W20577067382020 @default.
• W2057706738 countsByYear W20577067382021 @default.
• W2057706738 countsByYear W20577067382022 @default.
• W2057706738 countsByYear W20577067382023 @default.
• W2057706738 crossrefType "journal-article" @default.
• W2057706738 hasAuthorship W2057706738A5008950331 @default.
• W2057706738 hasAuthorship W2057706738A5017949708 @default.
• W2057706738 hasAuthorship W2057706738A5021264677 @default.
• W2057706738 hasAuthorship W2057706738A5055184323 @default.
• W2057706738 hasAuthorship W2057706738A5084875777 @default.
• W2057706738 hasBestOaLocation W20577067381 @default.
• W2057706738 hasConcept C122927707 @default.
• W2057706738 hasConcept C126322002 @default.
• W2057706738 hasConcept C134018914 @default.
• W2057706738 hasConcept C142536801 @default.
• W2057706738 hasConcept C161573976 @default.
• W2057706738 hasConcept C17093226 @default.
• W2057706738 hasConcept C171089720 @default.
• W2057706738 hasConcept C185592680 @default.
• W2057706738 hasConcept C25095133 @default.
• W2057706738 hasConcept C2776175234 @default.
• W2057706738 hasConcept C2776188179 @default.
• W2057706738 hasConcept C2777391703 @default.
• W2057706738 hasConcept C2777866211 @default.
• W2057706738 hasConcept C2777952866 @default.
• W2057706738 hasConcept C2779306644 @default.
• W2057706738 hasConcept C55493867 @default.
• W2057706738 hasConcept C71924100 @default.
• W2057706738 hasConcept C86803240 @default.
• W2057706738 hasConceptScore W2057706738C122927707 @default.
• W2057706738 hasConceptScore W2057706738C126322002 @default.
• W2057706738 hasConceptScore W2057706738C134018914 @default.
• W2057706738 hasConceptScore W2057706738C142536801 @default.
• W2057706738 hasConceptScore W2057706738C161573976 @default.
• W2057706738 hasConceptScore W2057706738C17093226 @default.
• W2057706738 hasConceptScore W2057706738C171089720 @default.
• W2057706738 hasConceptScore W2057706738C185592680 @default.
• W2057706738 hasConceptScore W2057706738C25095133 @default.
• W2057706738 hasConceptScore W2057706738C2776175234 @default.
• W2057706738 hasConceptScore W2057706738C2776188179 @default.
• W2057706738 hasConceptScore W2057706738C2777391703 @default.
• W2057706738 hasConceptScore W2057706738C2777866211 @default.
• W2057706738 hasConceptScore W2057706738C2777952866 @default.
• W2057706738 hasConceptScore W2057706738C2779306644 @default.
• W2057706738 hasConceptScore W2057706738C55493867 @default.
• W2057706738 hasConceptScore W2057706738C71924100 @default.
• W2057706738 hasConceptScore W2057706738C86803240 @default.
• W2057706738 hasIssue "5" @default.

• next