Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057722883> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2057722883 abstract "Abstract The decay kinetics of nicotine–DNA adducts and NNK–DNA adducts in mice liver after single dosing was studied by accelerator mass spectrometry (AMS). The decay is characterized by a two-stage process. The half-lives of nicotine–DNA adducts are 1.3 d (4–24 h) and 7.0 d (1–21 d), while for NNK–DNA adducts are 0.7 d (4–24 h) and 18.0 d (1–21 d). The relatively faster decay of nicotine–DNA adducts suggests that the genotoxicity of nicotine is weaker than that of NNK. The in vitro study shows that the metabolization of nicotine is necessary for the final formation of nicotine–DNA adducts, and nicotine Δ1′(5′) iminium ion is a probable metabolite species that binds to DNA molecule covalently." @default.
- W2057722883 created "2016-06-24" @default.
- W2057722883 creator A5005255883 @default.
- W2057722883 creator A5008609092 @default.
- W2057722883 creator A5017560580 @default.
- W2057722883 creator A5024032580 @default.
- W2057722883 creator A5057139613 @default.
- W2057722883 creator A5072308291 @default.
- W2057722883 creator A5074815658 @default.
- W2057722883 creator A5081561154 @default.
- W2057722883 date "2000-10-01" @default.
- W2057722883 modified "2023-09-27" @default.
- W2057722883 title "Decay kinetics of nicotine/NNK–DNA adducts in vivo studied by accelerator mass spectrometry" @default.
- W2057722883 cites W1973223683 @default.
- W2057722883 cites W1976007285 @default.
- W2057722883 cites W1993903290 @default.
- W2057722883 cites W2058073836 @default.
- W2057722883 cites W2091337764 @default.
- W2057722883 cites W2336522532 @default.
- W2057722883 cites W2488228444 @default.
- W2057722883 cites W2496580108 @default.
- W2057722883 doi "https://doi.org/10.1016/s0168-583x(00)00375-x" @default.
- W2057722883 hasPublicationYear "2000" @default.
- W2057722883 type Work @default.
- W2057722883 sameAs 2057722883 @default.
- W2057722883 citedByCount "2" @default.
- W2057722883 crossrefType "journal-article" @default.
- W2057722883 hasAuthorship W2057722883A5005255883 @default.
- W2057722883 hasAuthorship W2057722883A5008609092 @default.
- W2057722883 hasAuthorship W2057722883A5017560580 @default.
- W2057722883 hasAuthorship W2057722883A5024032580 @default.
- W2057722883 hasAuthorship W2057722883A5057139613 @default.
- W2057722883 hasAuthorship W2057722883A5072308291 @default.
- W2057722883 hasAuthorship W2057722883A5074815658 @default.
- W2057722883 hasAuthorship W2057722883A5081561154 @default.
- W2057722883 hasConcept C108204754 @default.
- W2057722883 hasConcept C121332964 @default.
- W2057722883 hasConcept C143425029 @default.
- W2057722883 hasConcept C148898269 @default.
- W2057722883 hasConcept C162356407 @default.
- W2057722883 hasConcept C169760540 @default.
- W2057722883 hasConcept C178790620 @default.
- W2057722883 hasConcept C185592680 @default.
- W2057722883 hasConcept C2778959862 @default.
- W2057722883 hasConcept C2779547902 @default.
- W2057722883 hasConcept C2781247443 @default.
- W2057722883 hasConcept C29730261 @default.
- W2057722883 hasConcept C43617362 @default.
- W2057722883 hasConcept C552990157 @default.
- W2057722883 hasConcept C55493867 @default.
- W2057722883 hasConcept C62520636 @default.
- W2057722883 hasConcept C86803240 @default.
- W2057722883 hasConceptScore W2057722883C108204754 @default.
- W2057722883 hasConceptScore W2057722883C121332964 @default.
- W2057722883 hasConceptScore W2057722883C143425029 @default.
- W2057722883 hasConceptScore W2057722883C148898269 @default.
- W2057722883 hasConceptScore W2057722883C162356407 @default.
- W2057722883 hasConceptScore W2057722883C169760540 @default.
- W2057722883 hasConceptScore W2057722883C178790620 @default.
- W2057722883 hasConceptScore W2057722883C185592680 @default.
- W2057722883 hasConceptScore W2057722883C2778959862 @default.
- W2057722883 hasConceptScore W2057722883C2779547902 @default.
- W2057722883 hasConceptScore W2057722883C2781247443 @default.
- W2057722883 hasConceptScore W2057722883C29730261 @default.
- W2057722883 hasConceptScore W2057722883C43617362 @default.
- W2057722883 hasConceptScore W2057722883C552990157 @default.
- W2057722883 hasConceptScore W2057722883C55493867 @default.
- W2057722883 hasConceptScore W2057722883C62520636 @default.
- W2057722883 hasConceptScore W2057722883C86803240 @default.
- W2057722883 hasLocation W20577228831 @default.
- W2057722883 hasOpenAccess W2057722883 @default.
- W2057722883 hasPrimaryLocation W20577228831 @default.
- W2057722883 hasRelatedWork W1652070020 @default.
- W2057722883 hasRelatedWork W1981329009 @default.
- W2057722883 hasRelatedWork W1982847729 @default.
- W2057722883 hasRelatedWork W2010720695 @default.
- W2057722883 hasRelatedWork W2018262668 @default.
- W2057722883 hasRelatedWork W2027656802 @default.
- W2057722883 hasRelatedWork W2031534611 @default.
- W2057722883 hasRelatedWork W2035016434 @default.
- W2057722883 hasRelatedWork W2035094242 @default.
- W2057722883 hasRelatedWork W2045516667 @default.
- W2057722883 hasRelatedWork W2053828723 @default.
- W2057722883 hasRelatedWork W2066008854 @default.
- W2057722883 hasRelatedWork W2073471394 @default.
- W2057722883 hasRelatedWork W2093683758 @default.
- W2057722883 hasRelatedWork W2094218174 @default.
- W2057722883 hasRelatedWork W2099929677 @default.
- W2057722883 hasRelatedWork W2101857650 @default.
- W2057722883 hasRelatedWork W2465870985 @default.
- W2057722883 hasRelatedWork W2797934237 @default.
- W2057722883 hasRelatedWork W3135141054 @default.
- W2057722883 isParatext "false" @default.
- W2057722883 isRetracted "false" @default.
- W2057722883 magId "2057722883" @default.
- W2057722883 workType "article" @default.