FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057788388> ?p ?o ?g. }

• W2057788388 endingPage "2128" @default.
• W2057788388 startingPage "2118" @default.
• W2057788388 abstract "Sensory feedback is critical for normal locomotion and adaptation to external perturbations during movement. Feedback provided by group Ia afferents influences motor output both directly through monosynaptic connections and indirectly through spinal interneuronal circuits. For example, the circuit responsible for reciprocal inhibition, which acts to prevent co-contraction of antagonist flexor and extensor muscles, is driven by Ia afferent feedback. Additionally, circuits mediating presynaptic inhibition can limit Ia afferent synaptic transmission onto central neuronal targets in a task-specific manner. These circuits can also be activated by stimulation of proprioceptive afferents. Rodent locomotion rapidly matures during postnatal development; therefore, we assayed the functional status of reciprocal and presynaptic inhibitory circuits of mice at birth and compared responses with observations made after 1 wk of postnatal development. Using extracellular physiological techniques from isolated and hemisected spinal cord preparations, we demonstrate that Ia afferent-evoked reciprocal inhibition is as effective at blocking antagonist motor neuron activation at birth as at 1 wk postnatally. In contrast, at birth conditioning stimulation of muscle nerve afferents failed to evoke presynaptic inhibition sufficient to block functional transmission at synapses between Ia afferents and motor neurons, even though dorsal root potentials could be evoked by stimulating the neighboring dorsal root. Presynaptic inhibition at this synapse was readily observed, however, at the end of the first postnatal week. These results indicate Ia afferent feedback from the periphery to central spinal circuits is only weakly gated at birth, which may provide enhanced sensitivity to peripheral feedback during early postnatal experiences." @default.
• W2057788388 created "2016-06-24" @default.
• W2057788388 creator A5058094660 @default.
• W2057788388 creator A5083049809 @default.
• W2057788388 date "2013-04-15" @default.
• W2057788388 modified "2023-09-23" @default.
• W2057788388 title "Early postnatal development of GABAergic presynaptic inhibition of Ia proprioceptive afferent connections in mouse spinal cord" @default.
• W2057788388 cites W1517975334 @default.
• W2057788388 cites W1542498459 @default.
• W2057788388 cites W1582490709 @default.
• W2057788388 cites W1669182664 @default.
• W2057788388 cites W1886140759 @default.
• W2057788388 cites W1964235903 @default.
• W2057788388 cites W1971869460 @default.
• W2057788388 cites W1973986892 @default.
• W2057788388 cites W1985640796 @default.
• W2057788388 cites W2001144285 @default.
• W2057788388 cites W2008292081 @default.
• W2057788388 cites W2009697267 @default.
• W2057788388 cites W2020447785 @default.
• W2057788388 cites W2021282412 @default.
• W2057788388 cites W2021388426 @default.
• W2057788388 cites W2022437069 @default.
• W2057788388 cites W2032957079 @default.
• W2057788388 cites W2039876881 @default.
• W2057788388 cites W2040562562 @default.
• W2057788388 cites W2045528648 @default.
• W2057788388 cites W2050903454 @default.
• W2057788388 cites W2052812788 @default.
• W2057788388 cites W2059483820 @default.
• W2057788388 cites W2060239276 @default.
• W2057788388 cites W2062005604 @default.
• W2057788388 cites W2063774868 @default.
• W2057788388 cites W2064022977 @default.
• W2057788388 cites W2073077262 @default.
• W2057788388 cites W2082421546 @default.
• W2057788388 cites W2097541219 @default.
• W2057788388 cites W2099450092 @default.
• W2057788388 cites W2102291467 @default.
• W2057788388 cites W2118717300 @default.
• W2057788388 cites W2120083721 @default.
• W2057788388 cites W2125870474 @default.
• W2057788388 cites W2127238274 @default.
• W2057788388 cites W2130549783 @default.
• W2057788388 cites W2131326854 @default.
• W2057788388 cites W2141290457 @default.
• W2057788388 cites W2146742867 @default.
• W2057788388 cites W2149700585 @default.
• W2057788388 cites W2162598008 @default.
• W2057788388 cites W2168307960 @default.
• W2057788388 cites W2169109050 @default.
• W2057788388 cites W2191752401 @default.
• W2057788388 cites W2196787566 @default.
• W2057788388 cites W2397203273 @default.
• W2057788388 cites W2411010078 @default.
• W2057788388 cites W2438937308 @default.
• W2057788388 cites W2502680694 @default.
• W2057788388 cites W4299640199 @default.
• W2057788388 doi "https://doi.org/10.1152/jn.00783.2012" @default.
• W2057788388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3628030" @default.
• W2057788388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23343895" @default.
• W2057788388 hasPublicationYear "2013" @default.
• W2057788388 type Work @default.
• W2057788388 sameAs 2057788388 @default.
• W2057788388 citedByCount "14" @default.
• W2057788388 countsByYear W20577883882014 @default.
• W2057788388 countsByYear W20577883882015 @default.
• W2057788388 countsByYear W20577883882016 @default.
• W2057788388 countsByYear W20577883882017 @default.
• W2057788388 countsByYear W20577883882018 @default.
• W2057788388 countsByYear W20577883882020 @default.
• W2057788388 countsByYear W20577883882021 @default.
• W2057788388 countsByYear W20577883882022 @default.
• W2057788388 crossrefType "journal-article" @default.
• W2057788388 hasAuthorship W2057788388A5058094660 @default.
• W2057788388 hasAuthorship W2057788388A5083049809 @default.
• W2057788388 hasBestOaLocation W20577883882 @default.
• W2057788388 hasConcept C127445978 @default.
• W2057788388 hasConcept C169760540 @default.
• W2057788388 hasConcept C170493617 @default.
• W2057788388 hasConcept C17077164 @default.
• W2057788388 hasConcept C200170125 @default.
• W2057788388 hasConcept C24998067 @default.
• W2057788388 hasConcept C2779177108 @default.
• W2057788388 hasConcept C2780775167 @default.
• W2057788388 hasConcept C55493867 @default.
• W2057788388 hasConcept C68000369 @default.
• W2057788388 hasConcept C86803240 @default.
• W2057788388 hasConcept C94487597 @default.
• W2057788388 hasConceptScore W2057788388C127445978 @default.
• W2057788388 hasConceptScore W2057788388C169760540 @default.
• W2057788388 hasConceptScore W2057788388C170493617 @default.
• W2057788388 hasConceptScore W2057788388C17077164 @default.
• W2057788388 hasConceptScore W2057788388C200170125 @default.
• W2057788388 hasConceptScore W2057788388C24998067 @default.
• W2057788388 hasConceptScore W2057788388C2779177108 @default.
• W2057788388 hasConceptScore W2057788388C2780775167 @default.
• W2057788388 hasConceptScore W2057788388C55493867 @default.

• next