Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057794049> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2057794049 endingPage "334" @default.
- W2057794049 startingPage "327" @default.
- W2057794049 abstract "The capacity of 41 different steroids to compete with progesterone for binding to reduced rabbit uteroglobin was used to determine the structural requirements in the steroid molecule relevant for its interaction with the active site of the protein. The binding of titrated estradiol-17β and testosterone was also studied directly, and both steroids were shown to bind to the same site as progesterone, although with lower affinity. There is a hydrophobic interaction of the protein with the α-side of the steroid molecule. Although minor modifications in the progesterone molecule can interfere with binding, the active site of uteroglobin appears to be able to accommodate different configurations of both the ring A and the side chain, including the phenolic A ring of estrogens and the C-17α-ethynyl side chain of some synthetic steroids. With the exception of estrogens, there is a good correlation between the ability of various steroids to bind to uteroglobin and their progestational activity." @default.
- W2057794049 created "2016-06-24" @default.
- W2057794049 creator A5029586324 @default.
- W2057794049 date "1976-05-01" @default.
- W2057794049 modified "2023-09-27" @default.
- W2057794049 title "Binding of steroids to uteroglobin" @default.
- W2057794049 cites W1508157020 @default.
- W2057794049 cites W1555625703 @default.
- W2057794049 cites W1970306075 @default.
- W2057794049 cites W1998200935 @default.
- W2057794049 cites W2007996185 @default.
- W2057794049 cites W2009571811 @default.
- W2057794049 cites W2026912546 @default.
- W2057794049 cites W2046676094 @default.
- W2057794049 cites W2051298488 @default.
- W2057794049 cites W2053041266 @default.
- W2057794049 cites W2077364513 @default.
- W2057794049 cites W2153039079 @default.
- W2057794049 cites W2276037416 @default.
- W2057794049 cites W2402629536 @default.
- W2057794049 cites W2410735879 @default.
- W2057794049 cites W2411614959 @default.
- W2057794049 cites W2416944625 @default.
- W2057794049 cites W2472680611 @default.
- W2057794049 doi "https://doi.org/10.1016/0022-4731(76)90091-1" @default.
- W2057794049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/933532" @default.
- W2057794049 hasPublicationYear "1976" @default.
- W2057794049 type Work @default.
- W2057794049 sameAs 2057794049 @default.
- W2057794049 citedByCount "64" @default.
- W2057794049 countsByYear W20577940492014 @default.
- W2057794049 countsByYear W20577940492020 @default.
- W2057794049 crossrefType "journal-article" @default.
- W2057794049 hasAuthorship W2057794049A5029586324 @default.
- W2057794049 hasConcept C104317684 @default.
- W2057794049 hasConcept C107824862 @default.
- W2057794049 hasConcept C134018914 @default.
- W2057794049 hasConcept C178790620 @default.
- W2057794049 hasConcept C181199279 @default.
- W2057794049 hasConcept C185592680 @default.
- W2057794049 hasConcept C204921945 @default.
- W2057794049 hasConcept C2779279991 @default.
- W2057794049 hasConcept C2780217633 @default.
- W2057794049 hasConcept C2780378348 @default.
- W2057794049 hasConcept C2780902042 @default.
- W2057794049 hasConcept C32909587 @default.
- W2057794049 hasConcept C41183919 @default.
- W2057794049 hasConcept C521977710 @default.
- W2057794049 hasConcept C55493867 @default.
- W2057794049 hasConcept C71240020 @default.
- W2057794049 hasConcept C71315377 @default.
- W2057794049 hasConcept C86803240 @default.
- W2057794049 hasConceptScore W2057794049C104317684 @default.
- W2057794049 hasConceptScore W2057794049C107824862 @default.
- W2057794049 hasConceptScore W2057794049C134018914 @default.
- W2057794049 hasConceptScore W2057794049C178790620 @default.
- W2057794049 hasConceptScore W2057794049C181199279 @default.
- W2057794049 hasConceptScore W2057794049C185592680 @default.
- W2057794049 hasConceptScore W2057794049C204921945 @default.
- W2057794049 hasConceptScore W2057794049C2779279991 @default.
- W2057794049 hasConceptScore W2057794049C2780217633 @default.
- W2057794049 hasConceptScore W2057794049C2780378348 @default.
- W2057794049 hasConceptScore W2057794049C2780902042 @default.
- W2057794049 hasConceptScore W2057794049C32909587 @default.
- W2057794049 hasConceptScore W2057794049C41183919 @default.
- W2057794049 hasConceptScore W2057794049C521977710 @default.
- W2057794049 hasConceptScore W2057794049C55493867 @default.
- W2057794049 hasConceptScore W2057794049C71240020 @default.
- W2057794049 hasConceptScore W2057794049C71315377 @default.
- W2057794049 hasConceptScore W2057794049C86803240 @default.
- W2057794049 hasIssue "5" @default.
- W2057794049 hasLocation W20577940491 @default.
- W2057794049 hasLocation W20577940492 @default.
- W2057794049 hasOpenAccess W2057794049 @default.
- W2057794049 hasPrimaryLocation W20577940491 @default.
- W2057794049 hasRelatedWork W1972342674 @default.
- W2057794049 hasRelatedWork W1991436142 @default.
- W2057794049 hasRelatedWork W1999256202 @default.
- W2057794049 hasRelatedWork W2002114468 @default.
- W2057794049 hasRelatedWork W2056224812 @default.
- W2057794049 hasRelatedWork W2057794049 @default.
- W2057794049 hasRelatedWork W2061616338 @default.
- W2057794049 hasRelatedWork W2066048039 @default.
- W2057794049 hasRelatedWork W2136082166 @default.
- W2057794049 hasRelatedWork W2951639401 @default.
- W2057794049 hasVolume "7" @default.
- W2057794049 isParatext "false" @default.
- W2057794049 isRetracted "false" @default.
- W2057794049 magId "2057794049" @default.
- W2057794049 workType "article" @default.