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- W2057795255 abstract "We review the effectiveness of androgen‐deprivation therapy (ADT) in the management of prostate cancer, and the effect that this treatment has on a patient’s quality of life (QoL), based on discussions held at a European symposium on the management of prostate cancer. The overall QoL is reduced in asymptomatic men, and there are known decreases in cognitive function, self‐esteem, libido and sexual function. Hot flashes are also a frequent problem. Prolonged ADT can lead to osteoporosis and subsequently fractures. Various effective methods exist to manage and minimize these side‐effects; some are specific to the side‐effect, whereas other more general methods include lifestyle changes, specific drugs and added hormonal manipulations. Intermittent ADT for patients taking luteinizing hormone‐releasing hormone agonists offers a promising method to reduce adverse effects, and possibly increases the time to androgen independence. Initial studies indicate that prostate‐specific antigen‐based progression with intermittent ADT is similar to that seen with continuous ADT, but there is a reduction in side‐effects, leading to an improvement in QoL." @default.
- W2057795255 created "2016-06-24" @default.
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- W2057795255 date "2006-06-08" @default.
- W2057795255 modified "2023-10-18" @default.
- W2057795255 title "Optimizing outcomes and quality of life in the hormonal treatment of prostate cancer" @default.
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- W2057795255 doi "https://doi.org/10.1111/j.1464-410x.2006.06176.x" @default.
- W2057795255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16566812" @default.
- W2057795255 hasPublicationYear "2006" @default.
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