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• W2057804938 abstract "The spatial distribution of the intracellular free Ca 2+ (Ca 2+ i ) rise elicited by different stimuli in bovine adrenal chromaffin cells was examined in single fura‐2‐loaded cells. In response to the potent secretagogues nicotine and high K + , Ca 2+ i was initially localized exclusively to the entire subplasmalemmal area of the cell. In response to the ineffective secretagogues, methacholine and muscarine, the rise in Ca 2+ i originated only in one pole of the cell and even at the peak of the response Ca 2+ was still generally restricted to this same area of the cell. These results suggest that the triggering of exocytosis from these cells requires a specific spatial distribution of Ca 2+ i ." @default.
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• W2057804938 date "1989-04-24" @default.
• W2057804938 modified "2023-10-17" @default.
• W2057804938 title "Spatial localization of the stimulus‐induced rise in cytosolic Ca²⁺ in bovine adrenal chromaffin cells" @default.
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• W2057804938 doi "https://doi.org/10.1016/0014-5793(89)81385-7" @default.
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